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Table 3 CD4+ distribution, level of differentiation and Cancer stage among HIV + participants (n = 22)

From: HIV serostatus and tumor differentiation among patients with cervical cancer at Bugando Medical Centre

Tumor characteristic

CD4+ count

Total

Mean CD4+ count ± SD

95% CI

p-value

≤350

>350

Cellular differentiation

      

Well

8 (66.7)

4 (33.3)

12 (100.0)

   

Moderate

5 (62.5)

3 (37.5)

8 (100.0)

   

Poor

2 (100.0)

0 (0)

2 (100.0)

   

Total

15 (68.2)

7 (31.8)

22 (100.0)

   

Overall CD4 count n = 22

   

315.0 ± 138.0

  

Well differentiated n = 12

   

318.8 ± 148.0

  

Moderately and poorly differentiated n = 10

   

310 ± 132.8

 

0.893*

Cancer stage

      

Early stage ( IA-IIA)

5 (55.6)

4 (44.4)

9 (100.0)

385.8 ± 170.4

354.8-516.7

0.042**

Late stage (IIB-IVB)

10 (76.9)

3 (23.1)

13 (100.0)

266.2 ± 87.5

213.3-319.0

 

Total

15 (68.2)

7 (31.8)

22 (100.0)

  

0.290 (Pearson)***

  1. Note: Number in brackets denotes%.
  2. * p-value from a t-test statistic comparing the mean CD4+ count between well differentiated and
  3. moderate and poorly differentiated tumor cell patients.
  4. ** p-value from a t-test statistic comparing the mean CD4+ count between early and late stage disease.
  5. ***p-value comparing women with CD4+ count ≤350/μL in early and late stage diseases.