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Table 2 Classification of 2-OG dependent dioxygenases

From: Distribution and prediction of catalytic domains in 2-oxoglutarate dependent dioxygenases

  Family (This work)*
REACTION  
 Demethylation ALKB, COLY
 Chlorinating CHLO
 Ring closure (cyclization) CYCL
 Desaturation CLAS, CYCL, FLAV
 Sulfate cleavage TDLP
 Ring expansion DACS
 Ether bond cleavage TFDA
 Hydroxylation NUHY(THYD,THYE,XANT), CP3H,CP4H,HP4H,ARGI,ASPA,ECTO,PHYT,GBBH,HYOS, PTLH
SUBSTRATE  
Amino acid/protein/derivative  
 Arginine ARGI
 Aspartyl; Asparagine ASPA
 Lysine COLY, HILY
 Proline CP3H,CP4H,HP4H
 Sulfonic acids (taurine), isethionate, taurocholate SULF (TDLP)
 gamma-butyrobetaine GBBH
 Collagen CP3H,CP4H,COLY
Nucleotide/ nucleoside  
 Thymidine THYD
 Thymine THYE
 Xanthine XANT
Misc. organic  
 Pro-clavaminate CLAS
 Deacetoxycephalosporin DACS
 Ectoine ECTO
 2 S-flavanones FLAV
 Gibberellins GIAC
 Hyoscyamine HYOS
 Phytanoyl-CoA PHYT
 PAA based pesticides/ herbicides TFDA
 Cyclopentane PTLH
 Aliphatic sulfate esters ATSK
 Translation in eukaryotes (eIF2α) OGFD
  1. (*) Note: Details of protein sequences used in this analysis (uniprot & PDB ids, references) are included as Additional file 1 : Table S1.