Table 2 Classification of 2-OG dependent dioxygenases
From: Distribution and prediction of catalytic domains in 2-oxoglutarate dependent dioxygenases
| Â | Family (This work)* |
|---|---|
REACTION | Â |
 Demethylation | ALKB, COLY |
 Chlorinating | CHLO |
 Ring closure (cyclization) | CYCL |
 Desaturation | CLAS, CYCL, FLAV |
 Sulfate cleavage | TDLP |
 Ring expansion | DACS |
 Ether bond cleavage | TFDA |
 Hydroxylation | NUHY(THYD,THYE,XANT), CP3H,CP4H,HP4H,ARGI,ASPA,ECTO,PHYT,GBBH,HYOS, PTLH |
SUBSTRATE | Â |
 Amino acid/protein/derivative |  |
 Arginine | ARGI |
 Aspartyl; Asparagine | ASPA |
 Lysine | COLY, HILY |
 Proline | CP3H,CP4H,HP4H |
 Sulfonic acids (taurine), isethionate, taurocholate | SULF (TDLP) |
 gamma-butyrobetaine | GBBH |
 Collagen | CP3H,CP4H,COLY |
 Nucleotide/ nucleoside |  |
 Thymidine | THYD |
 Thymine | THYE |
 Xanthine | XANT |
 Misc. organic |  |
 Pro-clavaminate | CLAS |
 Deacetoxycephalosporin | DACS |
 Ectoine | ECTO |
 2 S-flavanones | FLAV |
 Gibberellins | GIAC |
 Hyoscyamine | HYOS |
 Phytanoyl-CoA | PHYT |
 PAA based pesticides/ herbicides | TFDA |
 Cyclopentane | PTLH |
 Aliphatic sulfate esters | ATSK |
 Translation in eukaryotes (eIF2α) | OGFD |