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Figure 2 | BMC Research Notes

Figure 2

From: Robust non-linear differential equation models of gene expression evolution across Drosophila development

Figure 2

Parameter optimization for the gene expression networks. The standard deviation σ is given as a function of the total number of parameters p. The five curves correspond to the five model structures of eqs (5-9): dashed line: m N C p o l ; thick solid: m N N exp ; dashed-dotted line: m N C exp ; dotted line: m C N exp ; thin solid line: m lin . The number of parameters (p) depends on the connectivity per class (q) and the number of classes (C): p = (2q+4)C for m N C p o l , p = (2q+5)C for m N N exp , p = (q+4)C for m N C exp and m C N exp , and p = (q+1)C for m lin . The value of the minimum connectivity qm necessary to yield good data reproduction is indicated by a large circle. (a) Embryonic time series; the number of parameters p shown corresponds to connectivities q between 1 and 4; qm = 3; (b) full time series; the number of parameters p shown corresponds to connectivities q between 1 and 12; qm = 7.

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