Figure 2

Perspective plot of the log likelihood surface of the simulation pedigree data with γ = 0.003. The same likelihood polynomial as that of Figure1 is plotted with the γ penetrance estimate fixed at 0.003. The penetrance estimates are evaluated employing a parameter constraint 0 ≤ γ ≤ 0.01. The maximum appears near those of the other two estimates (α,β) = (0.875,0.759).