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Figure 2 | BMC Research Notes

Figure 2

From: Specific-mutational patterns of p53 gene in bladder transitional cell carcinoma among a group of Iraqi patients exposed to war environmental hazards

Figure 2

Immunohistochemical detection of p53 nuclear reactivity in transitional cell carcinoma (a) Invasive transitional cell carcinoma, poorly differentiated (Grade III) showing no detectible nuclear p53 immunostaining (Score (−), (10X)). (b) Papillary transitional cell carcinoma, well differentiated (Grade I) showing a few p53 immunoreactivty of tumor nuclei (Score (+/−), arrowed, (10X and 40X)). (c) Invasive transitional cell carcinoma, poorly differentiated (Grade II) showing heterogeneous p53 nuclear immunostaining (Score (+); arrowed,(40X)). (d) Papillary transitional cell carcinoma, well differentiated (Grade I) showing homogenous intense p53 nuclear immunostaining (Score (++); yellow arrow, (10X and 40X), (Red arrow indicates surrounding stromal and infiltrative lymphocytes with no detectible nuclear p53 immunostaining)).

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BMC Research Notes

ISSN: 1756-0500

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