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Table 1 Genes associated with ceramide metabolism in C. gigas from the in silico search

From: Characterization of genes involved in ceramide metabolism in the Pacific oyster (Crassostrea gigas)

Gene ID Gene description Species e-value
Cg_4852 Serine palmitoyltrasnferase-1 Pongo abelii 0
Cg_877 Acid ceramidase Rattus norvegicus 2E-146
Cg_14141 3-ketodihydrosphingosine reductase Mus musculus 5e-46
Cg_29918 Ceramide glucosyltransferase Xenopus tropicalis 9e-122
Cg_21728 Acid sphingomyelinase Mus musculus 5e-46
Cg_16356 Ceramide kinase Homo sapiens 1e-27
Cg_16726 Cerebrosidase Mus musculus 5e-139
Cg_17230 Neutral ceramidase Oryza sativa 5e-96
Cg_1560 Caspase 7 Homo sapiens 4e-10
Cg_23531 Caspase 8 Homo sapiens 8e-54
Cg_252 TNF receptor-associated factor 2 Mus musculus 1e-53
Cg_3248 TNF receptor-associated factor 3 Mus musculus 2e-30
Cg_31180 TNF receptor-associated factor 4 Homo sapiens 4e-39
Cg_6808 Neutral sphingomyelinase Caenorhabditis elegans 4e-10
Cg_20643 Dihydrosphingosine 1-phosphate phosphatase Schizosaccharomyces pombe 3e-9
Cg_26221 Sphingosine-1-phosphate phosphatase Mus musculus 8e-20
Cg_7888 Sphingosine-1-phosphate lyase Dictyostelium discoideum 6e-9
HS213433 Sphingomyelin synthase Homo sapiens 1e-100
HS185280 Ceramide synthase Mus musculus 5e-83
HQ425701 Inhibitor of apoptosis Crassostrea gigas -
HQ425703 Caspase 1 Crassostrea gigas -
HQ425705 Caspase 2 Crassostrea gigas -
HQ425699 Fas-associated receptor with Death Domain Crassostrea gigas -
  1. Genes associate with ceramide metabolism were identified in C. gigas by searching of publicly available databases. Sequences assembled from short read archive data and expressed sequence tags were given a Gene ID code that corresponds to the sequence in the Additional file1. For each of these contiguous sequences, the top BLASTx hit description, corresponding species, and e-value are provided. Two genes that matched to a single EST each in GenBank (sphingomyelin synthase and ceramide synthase) are denoted with their respective GenBank Accession Numbers since they are not represented as a contig of multiple ESTs. An additional four genes [GenBank: HQ425699, HQ425701, HQ425703, and HQ425705] have been previously characterized in C. gigas[20].