Nucleotide and phylogenetic analyses of the Chlamydia trachomatis ompA gene indicates it is a hotspot for mutation

Table 2 Nucleotide analyses of the constant (CD#) and variable (VD#) domains of the ompA gene

	# nt	#Δ nt sites	%Δ nt sites	d_N	d_S	d_N/d_S	ts/tv
CD1	255	19	7.45	0.008	0.092	0.09	1.6
CD2	165	43	26.06	0.024	0.927	0.03	2.7
CD3	189	52	27.51	0.019	0.596	0.03	6.3
CD4	150	26	17.33	0.014	0.421	0.03	2.4
CD5	168	15	8.93	0.004	0.123	0.03	2.1
CD1-5	927	155	16.72	0.013	0.314	0.04	2.0
VD1	66	58	87.88	0.797	0.962	0.83	0.4
VD2	66	51	77.27	0.640	0.983	0.65	0.9
VD3	42	19	45.24	0.135	0.491	0.27	0.9
VD4	93	58	62.37	0.281	0.648	0.43	1.1
VD1-4	267	186	69.66	0.404	1.204	0.34	0.7
ompA	1194	341	28.56	0.076	0.419	0.18	1.0

ISSN: 1756-0500