Figure 1

Energy per residue for the coiled-coil dimers taken up for the current analysis. The structures used for the study are regular coiled-coils with identified knobs-into-holes packing. A set of 118 structural entries were used for the analysis (energies are sorted from smallest to largest). The energies of 95% of these structures fall below -kJ/mol. Any coiled-coil structure with an energy better than - kJ/mol would be a stable coiled-coil, thus COILCHECK + energy could be used as a validating tool to identify the stability of the dimer