Figure 2

Homology model of Streptomyces sp. Mg1 ChiJ chitinase. A. Catalytically important residues are marked in red. Amino acids under strong and weak positive selection are shown in royal blue and dark green respectively. Variable regions from reverse conservation analysis are coloured in salmon and marked I-VII (I = 44–47, II = 75–80, III = 110–111, IV = 123–127, V = 178–185, VI = 200–203, VII = 312–327). B. Secondary structure elements of the enzyme are coloured differently. Side chains of co-evolving amino acids are shown in balls and sticks. Co-evolving groups of residues are illustrated in the same colour. Chito-tetraose is modelled to show the substrate-binding cleft.