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Table 1 Different tissue specific Unigene libraries employed in DDD

From: Lung Cancer Signature Biomarkers: tissue specific semantic similarity based clustering of Digital Differential Display (DDD) data

S. No.

Tissuetypes

No. of ESTlibraries

dbEST identification number

Respective Number of ESTs

1

Adipose

2

10983, 16445

8299, 1646

2

Adrenal gland

4

6791, 6792, 16377, 18302

4582, 1425, 2756, 10026

3

Tongue

4

12982, 18362, 18389, 18479

1116, 7730, 23564, 7420

4

Bladder

1

18307

8220

5

Blood

6

7037, 7038, 8975, 11923, 6824, 9724

1524, 1721, 4215, 6553, 7241, 9352

6

Bone

3

1124, 821, 16433

6209, 1337, 2615

7

Bone marrow

8

6975, 6976, 15949, 15950, 16412, 931, 10409, 10410

2459, 3424, 1379, 2707, 3623, 5336, 1798, 5231

8

Brain

36

1749, 16376, 16390, 18317, 18318, 18352, 18353, 18415, 18466, 14591, 14592, 186, 17380, 742, 16380, 18310, 18311, 16382, 16383, 18322, 1918, 5655, 6811, 6812, 8570, 19377, 14298, 13711, 13053, 536, 7209, 16384, 18319

1600, 1361, 13592, 2579, 15152, 43177, 24735, 23791, 6112, 31569, 15839, 1461, 1334, 18126, 5838, 4298, 3364, 41751, 40272, 2802, 3192, 16612, 7369, 8197, 2790, 3145, 19115, 44785, 1609, 7033, 3931, 4897, 5194, 2565, 25752

9

Eye

26

13915, 17747, 7316, 7315, 10273, 10287, 13901, 19465, 10274, 10281, 10280, 10288, 10279, 10284, 19471, 10285, 10286, 12093, 302, 303, 433, 10966, 10282, 10283, 16572, 13902

3739, 4253, 1836, 1294, 4005, 3543, 2785, 1334, 1595, 1479, 1115, 6010, 1469, 6719, 3043, 8344, 1199, 7816, 9190, 1732, 2174, 4531, 6279, 1185, 6097, 2946

10

Heart

8

15951, 16399, 18354, 18410, 16421, 18503, 16379, 16381

5307, 3284, 2667, 8670, 4000, 8502, 7220, 4698

11

Stomach

12

10299, 10301, 10302, 10305, 10306, 10310, 10311, 10324, 10325, 18488, 18529, 16432

1793, 2409, 1453, 2790, 1692, 1984, 6125, 5913, 1422, 8604, 2574, 3137

12

Testis

5

1752, 16441, 18476, 18517, 19376

6624, 2983, 46964, 44057, 40315

13

Thalamus

3

16437, 18348, 18349

3154, 29651, 23010

14

Thymus

6

16440, 18518, 18519, 18520, 13049, 18375

2365, 1044, 31967, 37541, 3477, 15983

15

Thyroid

3

889, 16408, 7004

1357, 4827, 3342

16

Breast

4

894, 895, 18305, 18475

1786, 6346, 2538, 8256

17

Cartilage

2

8936, 8940

4310, 3858

18

Cervix

2

18425, 18506

2674, 2619

19

Ear

2

371, 18222

12666, 3396

20

Intestine

13

840, 841, 842, 882, 16385, 18350, 18489, 16387, 16400, 17427, 18473, 16425, 18486

1499, 1704, 1759, 11996, 1817, 8191, 2619, 1351, 5536, 8199, 16855, 3403, 2545

21

Epidermis

4

20865, 21612, 7269, 21098

1627, 13186, 10681, 1135

22

Lung

11

10395, 16406, 16413, 16438, 18355, 18363, 18521, 10398, 11912, 18522, 18537

12545, 2448, 6839, 3327, 2565, 16156, 2677, 11510, 15695, 32590, 19278

23

Liver

11

1365, 12531, 12532, 12535, 12549, 12550, 13859, 16392, 18416, 18525, 18893

2302, 1607, 2315, 1136, 2425, 1561, 7537, 6856, 6550, 8424, 31921,

24

Mammary gland

3

6982, 16420, 16436

4561, 3502, 3371

25

Lymph

8

2709, 2710, 2711, 3718, 3719, 3720, 10312, 8613

3434, 3963, 1000, 9867, 1556, 1828, 7590, 1949

26

Teeth

1

12639

1576

27

Medulla

1

9725

9919

28

Muscle

4

530, 16391, 45, 18501

4271, 2154, 2485, 8276

29

Ovary

7

887, 6998, 18421, 18527, 5444, 12637, 12638

2341, 3678, 2300, 2543, 10294, 1050, 1031

30

Nose

2

358, 13908

1702, 24528

31

Placenta

14

13037, 16442, 507, 740, 6999, 10403, 10404, 10405, 10424, 10425, 16422, 17682, 18468, 18484, 13000

11885, 3501, 1370, 1172, 20941, 1862, 1166, 4260, 4517, 1271, 1529, 1032, 16852, 15843, 7344

32

Pancreas

6

16423, 422, 16960, 8840, 3884, 9821

4308, 1799, 13791, 60665, 1234, 17183

33

Prostate

8

888, 17392, 18469, 19880, 16424, 924, 928

1014, 1283, 16483, 41945, 2355, 7609, 1114, 1051

34

Uterus

6

1753, 16443, 18523, 18531, 18544, 12528

1645, 5121, 30124, 2486, 19168, 3510

35

Spleen

2

16431, 18474

2717, 33972

36

Salivary gland

1

16430

2336

37

Kidney

7

16393, 16395, 16410, 18374, 18377, 18524, 16429

5486, 5150, 3565, 17079, 2561, 15730, 1170

37

Pituitary

4

6828, 6829, 13019, 13737

3481, 1444, 7327, 1677

38

immune cells

6

1317, 17555, 17556, 8892, 12072, 12798

11447, 15272, 13685, 6112, 9223, 4548

39

Hair

4

21096, 21100, 21099, 21101

1269, 1288, 1298, 1543

40

Alimentary canal

2

18496, 18418

8371, 2586

41

Cancerous lung

8

1533, 10419, 537, 914, 14132, 14133, 14134, 14135

1377, 4401, 4173, 1850, 4365, 2121, 2847, 1560

  1. Differentially expressed normal lung tissue specific genes (DDD1) were identified from UniGene libraries representing 39 human normal tissues (251 libraries, 1903301 ESTs, S. No. 1–21, 23–40) and counterpart normal lung tissue (11 libraries, 125630 ESTs, S. No. 22 only). Differentially expressed lung tissue specific genes (DDD2) were identified from UniGene libraries representing lung cancer libraries (8 libraries, 22694 ESTs, S. No. 41 only) and counterpart normal lung tissue (11 libraries, 125630 ESTs, S. No. 22 only).
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BMC Research Notes

ISSN: 1756-0500

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