Table 1 Viral protein and peptide targets used for anti-arbovirus DNA aptamer development
Virus protein or peptide | Molec. Wt. | Commercial sources and amino acid sequence of peptides and applicable references |
|---|---|---|
Chikungunya E1a Peptide | 5,605 daltons (amino acids 200–250) | GenScript, Inc. (Piscataway, NJ): GDIQSRTPES KDVYANTQLVLQRPAVGTVHVPYSQAPSGF KYWLKERGAS; Santhosh et al. [13] and Pubmed Protein Sequence Database |
CCHF Altamura Gn 611 | 1,641 daltons | GenScript; TQ EGRGHVKL SRGSE Altamura et al., 2007 [16] |
CCHF 11E7a | 3,391 daltons | GenScript; GLKFASLTCTGCYACSSGISCKVRIHVDEPDE Ahmed, et al., 2005 and Altamura et al. 2007 [15, 16] |
CCHF 11E7b | 4,482 daltons | GenScript; VAASSSLMARKLEFGTDSTFKAFSAMPKTSLCFYIVEREY Ahmed, et al., 2005 and Altamura et al. 2007 [15, 16] |
CCHF 11E7c | 3,152 daltons | Genscript; EDTQ KCVNTKL EQPQSILIEHKGTIIGK Ahmed, et al., 2005 and Altamura et al. 2007 [15, 16] |
Recombinant dengue Type 1 | 41 kD E (envelope) antigen | Virostat, Inc. (Portland, ME) Product No. 8812 |
Recombinant dengue Type 2 | 15 kD E antigen | Virostat; Product No. 8813 |
Recombinant dengue Type 3 | 15 kD E antigen | Virostat; Product No. 8814 |
Recombinant dengue Type 4 | 15 kD E antigen | Virostat; Product No. 8815 |
TBEV CE/gE | Â | Feldan Bio Corp. (Quebec, Canada) Cat. No. FB03-80-149 |
WNV E Protein | ~ 42 kD E protein | GenWay Biotech (San Diego, CA) Cat. No. 10-511-248224 |