Active and total TGF-β levels in serum and inhibition of serum TGF-β by pan TGF-β neutralizing antibodies. A. Active and total TGF-β levels in serum. B Inhibition of total serum TGF-β in the absence or presence of 100 μg/ml of pan TGF-β neutralizing antibodies. RLU was inhibited by 92% with neutralizing antibody. Sample size: n = 6. NAB=neutralizing antibodies, RLU=relative luciferase unit, TGF-β=transforming growth factor-β.