Figure 1From: Sequence based analysis of U-2973, a cell line established from a double-hit B-cell lymphoma with concurrent MYC and BCL2 rearrangementsDetail of the t(8:12) translocations as validated by sequencing. This translocation has resulted in a possible heterozygous partial loss of CASC1, and has an unknown effect on MYC. LRMP has also been lost from the derivative chromosome 12. C and T denotes the direction of the centromere and telomere.Back to article page