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Table 2 Times from exposure to onset of stages and cull with experimental outcome in BSE-negative cattle

From: Bovine spongiform encephalopathy: the effect of oral exposure dose on attack rate and incubation period in cattle – an update

Animal identity Possible signs Probable signs Definite signs Cull Experimental outcome
1 g dose group      
CN939 49 –– –– 53 Spastic syndrome
CM933 56 –– –– 144*  
100 mg dose group      
CN950 –– –– –– 97 Urethral obstruction
CM921 –– –– –– 100 Hip injury
CN946 117 –– –– 144 Died, no cause identified
CM906 –– –– –– 145*  
CM914 –– –– –– 145*  
CN948 –– –– –– 145*  
CN949 –– –– –– 145*  
10 mg dose group      
CN952 –– –– –– 84 Indigestion?
CM915 –– –– –– 85 Metabolic disease
CM929 71 –– –– 101 Muscle trauma
CM919 –– –– –– 119 Osteoarthrosis
CM931 –– –– –– 123 Osteoarthrosis
CN941 65 –– –– 126 Recumbency, hypophosphataemia
CM904 53 –– –– 136 Recumbency, thyroid adenoma
CM899 –– –– –– 144*  
CM916 47 –– –– 144*  
CM924 138 –– –– 144* Compressive spinal cord lesion
CM913 –– –– –– 145*  
CM928 –– –– –– 145*  
CN943 –– –– –– 145*  
1 mg dose group      
CM922 64 –– –– 81 Renal failure
CM932 –– –– –– 103 Died, no cause identified
CM926 –– –– –– 104 Urethral obstruction
CN955 –– –– –– 109 Died – indigestion?
CM910 73 –– –– 112 Osteoarthrosis
CM907 –– –– –– 123 Spastic syndrome
CM920 94 –– –– 125 Osteoarthrosis
CM930 –– –– –– 136 Recumbency, meningeal tumour
CM905 62 –– –– 144*  
CN940 –– –– –– 144*  
CM896 –– –– –– 145*  
CM903 62 –– –– 145*  
CN937 106 –– –– 145* Hippocampal lesion (focal dysplasia)
CN945 127 –– –– 145*  
Undosed controls      
CM908 –– –– –– 39 Vertebral fracture
CM918 62 –– –– 97 Pleural mesothelioma
CM925 –– –– –– 59 Femoral fracture
CM856 61 –– –– 101 Septic arthritis
CM858 71 –– –– 103 Muscle injury, spastic syndrome
CM901 56 –– –– 125 Chronic enteritis (Johne’s disease)
CM927 135 –– –– 144 Found dead (indigestion?)
CM935 32 –– –– 145*  
CM859 117 –– –– 145*  
CM902 –– –– –– 145*  
  1. All cattle belonged to the second phase of the study.
  2. * Culled because of termination of study.
  3. Times are displayed in months. For controls, months are displayed as months after test group exposure.