TY - JOUR AU - Friedman, S. L. PY - 2003 DA - 2003// TI - Liver fibrosis – from bench to bedside JO - J Hepatol VL - 38 UR - https://doi.org/10.1016/S0168-8278(02)00429-4 DO - 10.1016/S0168-8278(02)00429-4 ID - Friedman2003 ER - TY - JOUR AU - Gressner, O. A. AU - Weiskirchen, R. AU - Gressner, A. M. PY - 2007 DA - 2007// TI - Biomarkers of liver fibrosis: clinical translation of molecular pathogenesis or based on liver-dependent malfunction tests JO - Clin Chim Acta VL - 381 UR - https://doi.org/10.1016/j.cca.2007.02.038 DO - 10.1016/j.cca.2007.02.038 ID - Gressner2007 ER - TY - JOUR AU - Bedossa, P. AU - Dargere, D. AU - Paradis, V. PY - 2003 DA - 2003// TI - Sampling variability of liver fibrosis in chronic hepatitis C JO - Hepatology VL - 38 UR - https://doi.org/10.1016/j.hep.2003.09.022 DO - 10.1016/j.hep.2003.09.022 ID - Bedossa2003 ER - TY - JOUR AU - Maharaj, B. AU - Maharaj, R. J. AU - Leary, W. P. AU - Cooppan, R. M. AU - Naran, A. D. AU - Pirie, D. PY - 1986 DA - 1986// TI - Sampling variability and its influence on the diagnostic yield of percutaneous needle biopsy of the liver JO - Lancet VL - 1 UR - https://doi.org/10.1016/S0140-6736(86)90883-4 DO - 10.1016/S0140-6736(86)90883-4 ID - Maharaj1986 ER - TY - JOUR AU - Veidal, S. S. AU - Bay-Jensen, A. C. AU - Tougas, G. AU - Karsdal, M. A. AU - Vainer, B. PY - 2010 DA - 2010// TI - Serum markers of liver fibrosis: combining the BIPED classification and the neo-epitope approach in the development of new biomarkers JO - Dis Markers VL - 28 UR - https://doi.org/10.1155/2010/548263 DO - 10.1155/2010/548263 ID - Veidal2010 ER - TY - BOOK AU - Kumar, V. A. A. K. F. N. PY - 2005 DA - 2005// TI - Tissue renewal and repair: regeneration, healing, and fibrosis. Pathologic basis of disease PB - Elsevier Saunders CY - Philadelphia, Pennsylvania, USA ID - Kumar2005 ER - TY - JOUR AU - Schuppan, D. PY - 1990 DA - 1990// TI - Structure of the extracellular matrix in normal and fibrotic liver: collagens and glycoproteins JO - Semin Liver Dis VL - 10 UR - https://doi.org/10.1055/s-2008-1040452 DO - 10.1055/s-2008-1040452 ID - Schuppan1990 ER - TY - JOUR AU - Schuppan, D. AU - Ruehl, M. AU - Somasundaram, R. AU - Hahn, E. G. PY - 2001 DA - 2001// TI - Matrix as a modulator of hepatic fibrogenesis JO - Semin Liver Dis VL - 21 UR - https://doi.org/10.1055/s-2001-17556 DO - 10.1055/s-2001-17556 ID - Schuppan2001 ER - TY - JOUR AU - Lochter, A. AU - Bissell, M. J. PY - 1999 DA - 1999// TI - An odyssey from breast to bone: multi-step control of mammary metastases and osteolysis by matrix metalloproteinases JO - APMIS VL - 107 UR - https://doi.org/10.1111/j.1699-0463.1999.tb01535.x DO - 10.1111/j.1699-0463.1999.tb01535.x ID - Lochter1999 ER - TY - JOUR AU - Karsdal, M. A. AU - Madsen, S. H. AU - Christiansen, C. AU - Henriksen, K. AU - Fosang, A. J. AU - Sondergaard, B. C. PY - 2008 DA - 2008// TI - Cartilage degradation is fully reversible in the presence of aggrecanase but not matrix metalloproteinase activity JO - Arthritis Res Ther VL - 10 UR - https://doi.org/10.1186/ar2434 DO - 10.1186/ar2434 ID - Karsdal2008 ER - TY - JOUR AU - Karsdal, M. A. AU - Henriksen, K. AU - Leeming, D. J. AU - Mitchell, P. AU - Duffin, K. AU - Barascuk, N. PY - 2009 DA - 2009// TI - Biochemical markers and the FDA Critical Path: how biomarkers may contribute to the understanding of pathophysiology and provide unique and necessary tools for drug development JO - Biomarkers VL - 14 UR - https://doi.org/10.1080/13547500902777608 DO - 10.1080/13547500902777608 ID - Karsdal2009 ER - TY - JOUR AU - Gelse, K. AU - Poschl, E. AU - Aigner, T. PY - 2003 DA - 2003// TI - Collagens–structure, function, and biosynthesis JO - Adv Drug Deliv Rev VL - 55 UR - https://doi.org/10.1016/j.addr.2003.08.002 DO - 10.1016/j.addr.2003.08.002 ID - Gelse2003 ER - TY - JOUR AU - Garnero, P. AU - Ferreras, M. AU - Karsdal, M. A. AU - Nicamhlaoibh, R. AU - Risteli, J. AU - Borel, O. PY - 2003 DA - 2003// TI - The type I collagen fragments ICTP and CTX reveal distinct enzymatic pathways of bone collagen degradation JO - J Bone Miner Res VL - 18 UR - https://doi.org/10.1359/jbmr.2003.18.5.859 DO - 10.1359/jbmr.2003.18.5.859 ID - Garnero2003 ER - TY - JOUR AU - Gressner, A. M. AU - Weiskirchen, R. PY - 2006 DA - 2006// TI - Modern pathogenetic concepts of liver fibrosis suggest stellate cells and TGF-beta as major players and therapeutic targets JO - J Cell Mol Med VL - 10 UR - https://doi.org/10.1111/j.1582-4934.2006.tb00292.x DO - 10.1111/j.1582-4934.2006.tb00292.x ID - Gressner2006 ER - TY - JOUR AU - Hemmann, S. AU - Graf, J. AU - Roderfeld, M. AU - Roeb, E. PY - 2007 DA - 2007// TI - Expression of MMPs and TIMPs in liver fibrosis - a systematic review with special emphasis on anti-fibrotic strategies JO - J Hepatol VL - 46 UR - https://doi.org/10.1016/j.jhep.2007.02.003 DO - 10.1016/j.jhep.2007.02.003 ID - Hemmann2007 ER - TY - JOUR AU - Kirimlioglu, H. AU - Kirimlioglu, V. AU - Yilmaz, S. PY - 2008 DA - 2008// TI - Expression of matrix metalloproteinases 2 and 9 in donor liver, cirrhotic liver, and acute rejection after human liver transplantation JO - Transplant Proc VL - 40 UR - https://doi.org/10.1016/j.transproceed.2008.09.033 DO - 10.1016/j.transproceed.2008.09.033 ID - Kirimlioglu2008 ER - TY - JOUR AU - Gieling, R. G. AU - Wallace, K. AU - Han, Y. P. PY - 2009 DA - 2009// TI - Interleukin-1 participates in the progression from liver injury to fibrosis JO - Am J Physiol Gastrointest Liver Physiol VL - 296 UR - https://doi.org/10.1152/ajpgi.90564.2008 DO - 10.1152/ajpgi.90564.2008 ID - Gieling2009 ER - TY - JOUR AU - Olsen, A. K. AU - Sondergaard, B. C. AU - Byrjalsen, I. AU - Tanko, L. B. AU - Christiansen, C. AU - Muller, A. PY - 2007 DA - 2007// TI - Anabolic and catabolic function of chondrocyte ex vivo is reflected by the metabolic processing of type II collagen JO - Osteoarthritis Cartilage VL - 15 UR - https://doi.org/10.1016/j.joca.2006.08.015 DO - 10.1016/j.joca.2006.08.015 ID - Olsen2007 ER - TY - JOUR AU - Bay-Jensen, A. C. AU - Liu, Q. AU - Byrjalsen, I. AU - Li, Y. AU - Wang, J. AU - Pedersen, C. PY - 2011 DA - 2011// TI - Enzyme-linked immunosorbent assay (ELISAs) for metalloproteinase derived type II collagen neoepitope, CIIM–increased serum CIIM in subjects with severe radiographic osteoarthritis JO - Clin Biochem VL - 44 UR - https://doi.org/10.1016/j.clinbiochem.2011.01.001 DO - 10.1016/j.clinbiochem.2011.01.001 ID - Bay-Jensen2011 ER - TY - JOUR AU - Leeming, D. J. AU - Larsen, D. V. AU - Zhang, C. AU - Hi, Y. AU - Veidal, S. S. AU - Nielsen, R. H. PY - 2010 DA - 2010// TI - Enzyme-linked immunosorbent serum assays (ELISAs) for rat and human N-terminal pro-peptide of collagen type I (PINP)–assessment of corresponding epitopes JO - Clin Biochem VL - 43 UR - https://doi.org/10.1016/j.clinbiochem.2010.07.025 DO - 10.1016/j.clinbiochem.2010.07.025 ID - Leeming2010 ER - TY - JOUR AU - Vassiliadis, E. AU - Larsen, D. V. AU - Clausen, R. E. AU - Veidal, S. S. AU - Barascuk, N. AU - Larsen, L. PY - 2011 DA - 2011// TI - Measurement of CO3-610, a Potential Liver Biomarker Derived from Matrix Metalloproteinase-9 Degradation of Collagen Type III, in a Rat Model of Reversible Carbon-Tetrachloride-Induced Fibrosis JO - Biomark Insights VL - 6 UR - https://doi.org/10.4137/BMI.S6347 DO - 10.4137/BMI.S6347 ID - Vassiliadis2011 ER - TY - JOUR AU - Barascuk, N. AU - Vassiliadis, E. AU - Larsen, L. AU - Wang, J. AU - Zheng, Q. AU - Xing, R. PY - 2011 DA - 2011// TI - Development and validation of an enzyme-linked immunosorbent assay for the quantification of a specific MMP-9 mediated degradation fragment of type III collagen-A novel biomarker of atherosclerotic plaque remodeling JO - Clin Biochem VL - 44 UR - https://doi.org/10.1016/j.clinbiochem.2011.04.004 DO - 10.1016/j.clinbiochem.2011.04.004 ID - Barascuk2011 ER - TY - JOUR AU - Barascuk, N. AU - Veidal, S. S. AU - Larsen, L. AU - Larsen, D. V. AU - Larsen, M. R. AU - Wang, J. PY - 2010 DA - 2010// TI - A novel assay for extracellular matrix remodeling associated with liver fibrosis: An enzyme-linked immunosorbent assay (ELISA) for a MMP-9 proteolytically revealed neo-epitope of type III collagen JO - Clin Biochem VL - 43 UR - https://doi.org/10.1016/j.clinbiochem.2010.03.012 DO - 10.1016/j.clinbiochem.2010.03.012 ID - Barascuk2010 ER - TY - JOUR AU - Vassiliadis, E. AU - Veidal, S. S. AU - Barascuk, N. AU - Mullick, J. B. AU - Clausen, R. E. AU - Larsen, L. PY - 2011 DA - 2011// TI - Measurement of matrix metalloproteinase 9-mediated collagen type III degradation fragment as a marker of skin fibrosis JO - BMC Dermatol VL - 11 UR - https://doi.org/10.1186/1471-5945-11-6 DO - 10.1186/1471-5945-11-6 ID - Vassiliadis2011 ER - TY - JOUR AU - Weiler-Normann, C. AU - Herkel, J. AU - Lohse, A. W. PY - 2007 DA - 2007// TI - Mouse models of liver fibrosis JO - Z Gastroenterol VL - 45 UR - https://doi.org/10.1055/s-2006-927387 DO - 10.1055/s-2006-927387 ID - Weiler-Normann2007 ER - TY - JOUR AU - Sondergaard, B. C. AU - Wulf, H. AU - Henriksen, K. AU - Schaller, S. AU - Oestergaard, S. AU - Qvist, P. PY - 2006 DA - 2006// TI - Calcitonin directly attenuates collagen type II degradation by inhibition of matrix metalloproteinase expression and activity in articular chondrocytes JO - Osteoarthritis Cartilage VL - 14 UR - https://doi.org/10.1016/j.joca.2006.01.014 DO - 10.1016/j.joca.2006.01.014 ID - Sondergaard2006 ER - TY - JOUR AU - Sondergaard, B. C. AU - Henriksen, K. AU - Wulf, H. AU - Oestergaard, S. AU - Schurigt, U. AU - Brauer, R. PY - 2006 DA - 2006// TI - Relative contribution of matrix metalloprotease and cysteine protease activities to cytokine-stimulated articular cartilage degradation JO - Osteoarthritis Cartilage VL - 14 UR - https://doi.org/10.1016/j.joca.2006.01.016 DO - 10.1016/j.joca.2006.01.016 ID - Sondergaard2006 ER - TY - JOUR AU - Friedman, S. L. PY - 2008 DA - 2008// TI - Hepatic stellate cells: protean, multifunctional, and enigmatic cells of the liver JO - Physiol Rev VL - 88 UR - https://doi.org/10.1152/physrev.00013.2007 DO - 10.1152/physrev.00013.2007 ID - Friedman2008 ER - TY - JOUR AU - Ekins, S. PY - 1996 DA - 1996// TI - Past, present, and future applications of precision-cut liver slices for in vitro xenobiotic metabolism JO - Drug Metab Rev VL - 28 UR - https://doi.org/10.3109/03602539608994019 DO - 10.3109/03602539608994019 ID - Ekins1996 ER - TY - JOUR AU - Karsdal, M. A. AU - Sumer, E. U. AU - Wulf, H. AU - Madsen, S. H. AU - Christiansen, C. AU - Fosang, A. J. PY - 2007 DA - 2007// TI - Induction of increased cAMP levels in articular chondrocytes blocks matrix metalloproteinase-mediated cartilage degradation, but not aggrecanase-mediated cartilage degradation JO - Arthritis Rheum VL - 56 UR - https://doi.org/10.1002/art.22599 DO - 10.1002/art.22599 ID - Karsdal2007 ER - TY - JOUR AU - Van de Bovenkamp, M. AU - Groothuis, G. M. AU - Draaisma, A. L. AU - Merema, M. T. AU - Bezuijen, J. I. AU - van Gils, M. J. PY - 2005 DA - 2005// TI - Precision-cut liver slices as a new model to study toxicity-induced hepatic stellate cell activation in a physiologic milieu JO - Toxicol Sci VL - 85 UR - https://doi.org/10.1093/toxsci/kfi127 DO - 10.1093/toxsci/kfi127 ID - Van de Bovenkamp2005 ER - TY - JOUR AU - Al-Nasiry, S. AU - Geusens, N. AU - Hanssens, M. AU - Luyten, C. AU - Pijnenborg, R. PY - 2007 DA - 2007// TI - The use of Alamar Blue assay for quantitative analysis of viability, migration and invasion of choriocarcinoma cells JO - Hum Reprod VL - 22 UR - https://doi.org/10.1093/humrep/dem011 DO - 10.1093/humrep/dem011 ID - Al-Nasiry2007 ER - TY - JOUR AU - Van de Bovenkamp, M. AU - Groothuis, G. M. AU - Meijer, D. K. AU - Olinga, P. PY - 2007 DA - 2007// TI - Liver fibrosis in vitro: cell culture models and precision-cut liver slices JO - Toxicol In Vitro VL - 21 UR - https://doi.org/10.1016/j.tiv.2006.12.009 DO - 10.1016/j.tiv.2006.12.009 ID - Van de Bovenkamp2007 ER - TY - JOUR AU - Vickers, A. E. AU - Fisher, R. L. PY - 2005 DA - 2005// TI - Precision-cut organ slices to investigate target organ injury JO - Expert Opin Drug Metab Toxicol VL - 1 UR - https://doi.org/10.1517/17425255.1.4.687 DO - 10.1517/17425255.1.4.687 ID - Vickers2005 ER - TY - JOUR AU - Olinga, P. AU - Groen, K. AU - Hof, I. H. AU - De, K. R. AU - Koster, H. J. AU - Leeman, W. R. PY - 1997 DA - 1997// TI - Comparison of five incubation systems for rat liver slices using functional and viability parameters JO - J Pharmacol Toxicol Methods VL - 38 UR - https://doi.org/10.1016/S1056-8719(97)00060-9 DO - 10.1016/S1056-8719(97)00060-9 ID - Olinga1997 ER - TY - JOUR AU - Olinga, P. AU - Merema, M. T. AU - de Jager, M. H. AU - Derks, F. AU - Melgert, B. N. AU - Moshage, H. PY - 2001 DA - 2001// TI - Rat liver slices as a tool to study LPS-induced inflammatory response in the liver JO - J Hepatol VL - 35 UR - https://doi.org/10.1016/S0168-8278(01)00103-9 DO - 10.1016/S0168-8278(01)00103-9 ID - Olinga2001 ER - TY - JOUR AU - Guyot, C. AU - Combe, C. AU - Balabaud, C. AU - Bioulac-Sage, P. AU - Desmouliere, A. PY - 2007 DA - 2007// TI - Fibrogenic cell fate during fibrotic tissue remodelling observed in rat and human cultured liver slices JO - J Hepatol VL - 46 UR - https://doi.org/10.1016/j.jhep.2006.08.013 DO - 10.1016/j.jhep.2006.08.013 ID - Guyot2007 ER - TY - JOUR AU - Veidal, S. S. AU - Vassiliadis, E. AU - Barascuk, N. AU - Zhang, C. AU - Segovia-Silvestre, T. AU - Klickstein, L. PY - 2010 DA - 2010// TI - Matrix metalloproteinase-9-mediated type III collagen degradation as a novel serological biochemical marker for liver fibrogenesis JO - Liver Int VL - 30 UR - https://doi.org/10.1111/j.1478-3231.2010.02309.x DO - 10.1111/j.1478-3231.2010.02309.x ID - Veidal2010 ER - TY - JOUR AU - Segovia-Silvestre, T. AU - Reichenbach, V. AU - Fernandez-Varo, G. AU - Vassiliadis, E. AU - Barascuk, N. AU - Morales-Ruiz, M. PY - 2011 DA - 2011// TI - Circulating CO3-610, a degradation product of collagen III, closely reflects liver collagen and portal pressure in rats with fibrosis JO - Fibrogenesis Tissue Repair VL - 4 UR - https://doi.org/10.1186/1755-1536-4-19 DO - 10.1186/1755-1536-4-19 ID - Segovia-Silvestre2011 ER - TY - JOUR AU - Fantidis, P. PY - 2010 DA - 2010// TI - The role of intracellular 3'5'-cyclic adenosine monophosphate (cAMP) in atherosclerosis JO - Curr Vasc Pharmacol VL - 8 UR - https://doi.org/10.2174/157016110791330843 DO - 10.2174/157016110791330843 ID - Fantidis2010 ER - TY - CHAP AU - Schippers, M. AU - Schmidt, M. AU - Spijkers, K. AU - Post, E. AU - Beljaars, L. AU - Poelstra, K. PY - 2012 DA - 2012// TI - 40th Keystone Symposia on Molecular and Cellular Biology BT - Prostaglandin E2-activated Epac-1 expression reduces collagen deposition in CCl4-induced liver fibrosis in mice ID - Schippers2012 ER - TY - JOUR AU - Schurigt, U. AU - Hummel, K. M. AU - Petrow, P. K. AU - Gajda, M. AU - Stockigt, R. AU - Middel, P. PY - 2008 DA - 2008// TI - Cathepsin K deficiency partially inhibits, but does not prevent, bone destruction in human tumor necrosis factor-transgenic mice JO - Arthritis Rheum VL - 58 UR - https://doi.org/10.1002/art.23224 DO - 10.1002/art.23224 ID - Schurigt2008 ER - TY - JOUR AU - Iredale, J. P. AU - Benyon, R. C. AU - Pickering, J. AU - McCullen, M. AU - Northrop, M. AU - Pawley, S. PY - 1998 DA - 1998// TI - Mechanisms of spontaneous resolution of rat liver fibrosis. Hepatic stellate cell apoptosis and reduced hepatic expression of metalloproteinase inhibitors JO - J Clin Invest VL - 102 UR - https://doi.org/10.1172/JCI1018 DO - 10.1172/JCI1018 ID - Iredale1998 ER - TY - JOUR AU - Woessner, J. F. PY - 1991 DA - 1991// TI - Matrix metalloproteinases and their inhibitors in connective tissue remodeling JO - FASEB J VL - 5 ID - Woessner1991 ER - TY - JOUR AU - Han, Y. P. PY - 2006 DA - 2006// TI - Matrix metalloproteinases, the pros and cons, in liver fibrosis JO - J Gastroenterol Hepatol VL - 21 UR - https://doi.org/10.1111/j.1440-1746.2006.04586.x DO - 10.1111/j.1440-1746.2006.04586.x ID - Han2006 ER - TY - JOUR AU - Kossakowska, A. E. AU - Edwards, D. R. AU - Lee, S. S. AU - Urbanski, L. S. AU - Stabbler, A. L. AU - Zhang, C. L. PY - 1998 DA - 1998// TI - Altered balance between matrix metalloproteinases and their inhibitors in experimental biliary fibrosis JO - Am J Pathol VL - 153 UR - https://doi.org/10.1016/S0002-9440(10)65703-3 DO - 10.1016/S0002-9440(10)65703-3 ID - Kossakowska1998 ER - TY - JOUR AU - Takahara, T. AU - Furui, K. AU - Funaki, J. AU - Nakayama, Y. AU - Itoh, H. AU - Miyabayashi, C. PY - 1995 DA - 1995// TI - Increased expression of matrix metalloproteinase-II in experimental liver fibrosis in rats JO - Hepatology VL - 21 UR - https://doi.org/10.1002/hep.1840210328 DO - 10.1002/hep.1840210328 ID - Takahara1995 ER - TY - JOUR AU - Lee, U. E. AU - Friedman, S. L. PY - 2011 DA - 2011// TI - Mechanisms of hepatic fibrogenesis JO - Best Pract Res Clin Gastroenterol VL - 25 UR - https://doi.org/10.1016/j.bpg.2011.02.005 DO - 10.1016/j.bpg.2011.02.005 ID - Lee2011 ER - TY - JOUR AU - Jiao, J. AU - Sastre, D. AU - Fiel, M. I. AU - Lee, U. E. AU - Ghiassi-Nejad, Z. AU - Ginhoux, F. PY - 2012 DA - 2012// TI - Dendritic cell regulation of carbon tetrachloride-induced murine liver fibrosis regression JO - Hepatology VL - 55 UR - https://doi.org/10.1002/hep.24621 DO - 10.1002/hep.24621 ID - Jiao2012 ER - TY - JOUR AU - Karsdal, M. A. AU - Larsen, L. AU - Engsig, M. T. AU - Lou, H. AU - Ferreras, M. AU - Lochter, A. PY - 2002 DA - 2002// TI - Matrix metalloproteinase-dependent activation of latent transforming growth factor-beta controls the conversion of osteoblasts into osteocytes by blocking osteoblast apoptosis JO - J Biol Chem VL - 277 UR - https://doi.org/10.1074/jbc.M207205200 DO - 10.1074/jbc.M207205200 ID - Karsdal2002 ER - TY - JOUR AU - Gonzalez, R. J. AU - Tarloff, J. B. PY - 2001 DA - 2001// TI - Evaluation of hepatic subcellular fractions for Alamar blue and MTT reductase activity JO - Toxicol In Vitro VL - 15 UR - https://doi.org/10.1016/S0887-2333(01)00014-5 DO - 10.1016/S0887-2333(01)00014-5 ID - Gonzalez2001 ER - TY - JOUR AU - Van de Bovenkamp, M. AU - Groothuis, G. M. AU - Meijer, D. K. AU - Slooff, M. J. AU - Olinga, P. PY - 2006 DA - 2006// TI - Human liver slices as an in vitro model to study toxicity-induced hepatic stellate cell activation in a multicellular milieu JO - Chem Biol Interact VL - 162 UR - https://doi.org/10.1016/j.cbi.2006.05.006 DO - 10.1016/j.cbi.2006.05.006 ID - Van de Bovenkamp2006 ER -