Table 1 Biomarkers before and after gastric bypass surgery by menopausal status
From: Breast cancer biomarkers predict weight loss after gastric bypass surgery
Variable | Menopausal Status | Value | Months since surgery | |||
|---|---|---|---|---|---|---|
| Â | Â | Â | 0 | 3 | 6 | 12 |
Nipple aspirate fluid (n)PSA (ng/g) p value ≤ .001, ***; p value ≤ .01, **; p value ≤ .05, *, compared to baseline | Pre- menopausal | Mean | 2514.0 | 1080.3 | 4942.2 | 1379.4 |
| Â | Â | Median | 405.1 | 166.7 | 653.2 | 586.9 |
| Â | Â | StDev | 4049.7 | 2406.9 | 11470.0 | 2026.8 |
| Â | Â | Samples | 15 | 13 | 12 | 7 |
| Â | Post- menopausal | Mean | 1266.4 | 731.7 | 1130.5 | 643.2 |
| Â | Â | Median | 200.0 | 109.4 | 575.4 | 399.1 |
| Â | Â | StDev | 2831.6 | 1356.4 | 1748.7 | 1006.8 |
| Â | Â | Samples | 9 | 8 | 8 | 8 |
| Â | Total sample | Mean | 2046.1 | 947.5 | 3417.5 | 986.7 |
| Â | Â | Median | 315.7 | 144.3 | 653.2 | 510 |
| Â | Â | StDev | 3626.6 | 2037.1 | 8998.0 | 1553.0 |
| Â | Â | Samples | 24 | 21 | 20 | 15 |
n- adiponectin (ng/mL) p value ≤ .001, ***; p value ≤ .01, **; p value ≤ .05, *, compared to baseline | Pre- menopausal | Mean | 778.7 | 1118.9 | 1164.5 | 1293.7 |
| Â | Â | Median | 471.8 | 617.1* | 808.8* | 638.2 |
| Â | Â | StDev | 746.8 | 961.3 | 1091.9 | 1346.2 |
| Â | Â | Samples | 14 | 12 | 11 | 9 |
| Â | Post- menopausal | Mean | 1310.3 | 1323.1 | 1482.6 | 2056.8 |
| Â | Â | Median | 984.2 | 1168.5 | 1006.0 | 1204.2 |
| Â | Â | StDev | 992.9 | 903.0 | 1169.6 | 1933.4 |
| Â | Â | Samples | 8 | 6 | 8 | 7 |
| Â | Total sample | Mean | 972.0 | 1186.9 | 1298.5 | 1627.5 |
| Â | Â | Median | 690.9 | 817.1 | 808.8 | 894.8 |
| Â | Â | StDev | 861.6 | 920.6 | 1104.7 | 1617.0 |
| Â | Â | Samples | 22 | 18 | 19 | 16 |
Serum (s)- adiponectin (ng/mL) p value ≤ .001, ***; p value ≤ .01, **; p value ≤ .05,*, compared to baseline | Pre- menopausal | Mean | 7245.4 | 9090.9 | 10427.7 | 12103.8 |
| Â | Â | Median | 7366.0 | 9113.0*** | 9846.5*** | 12008.3* |
| Â | Â | StDev | 2706.8 | 2997.5 | 3119.2 | 3551.7 |
| Â | Â | Samples | 18 | 17 | 17 | 8 |
| Â | Post- menopausal | Mean | 11925.6 | 11388.0 | 12370.0 | 13646.4 |
| Â | Â | Median | 8900.5 | 10968.0 | 10429.5 | 11944.5 |
| Â | Â | StDev | 7252.0 | 4829.7 | 4635.6 | 5408.2 |
| Â | Â | Samples | 10 | 9 | 9 | 7 |
| Â | Total sample | Mean | 8916.9 | 9886.1 | 11100.0 | 12823.6 |
| Â | Â | Median | 7406.3 | 9368.0** | 10138.0** | 11944.5** |
| Â | Â | StDev | 5230.6 | 3802.2 | 3740.5 | 4413.3 |
| Â | Â | Samples | 28 | 26 | 26 | 15 |