Domain organisation of representative WHAMM proteins. A colour key to the domain names and symbols is given on the right except for the WMD domain and the poly-proline region (PPR) that are coloured in dark green and yellow, respectively. The class-2 and class-3 WHAMM homologs encode insertions in the WMD domain. For Hs WHAMM2 the insertion is symbolized by light-green bars. The sequence logo illustrates the sequence conservation within the multiple sequence alignments of the previously supposed third WH2 domain in class-2 WHAMM homologs. However, the sequence is not in accordance with the consensus WH2 sequence motif. Species abbreviation: Hs = Homo sapiens.