Table 3 Predicted microRNAs targeting rat GABA receptor subunits by TargetScan and miRanda
GABA receptor subunits | Entrez Gene symbol | Lengths of 3'-UTR in TargetScan (v5.2) | Conserved microRNAs targeting to GABA receptors predicted by TargetScan (v5.2) | Lengths of 3'-UTR in miRanda | Conserved microRNAs targeting to GABA receptors predicted by miRanda |
|---|---|---|---|---|---|
α1 | GABRA1 | 2017 | miR-208/208ab, | 2018 | miR-129 (2), miR-130b, miR-136, miR-137, miR-148b-3p, |
miR-499/499-5p, miR-181, | miR-150, miR-152, miR-181a (2) bc (3) d, miR-182, | ||||
miR-216/216a, miR-137, | miR-186, miR-203 (2), miR-210, miR-216a, miR-26ab, | ||||
miR-203 | miR-30acde, miR-30b-5p, miR-320, miR-340-5p, miR-361, | ||||
miR-374, miR-375, miR-376c, miR-377, miR-384-5p, | |||||
miR-410, miR-433, miR-488 (2), miR-539, miR-874 | |||||
α2 | GABRA2 | 747 | 0 | NA | NA |
α3 | GABRA3 | 0 | 0 | NA | NA |
α4 | GABRA4 | 7478 | 0 | 88 | miR-186, miR-200bc, miR-203, miR-429, miR-495 |
α5 | GABRA5 | 586 | 0 | 880 | miR-124, miR-132, miR-133ab, miR-195, miR-212, miR-223, |
miR-30acde, miR-30b-5p, miR-322, miR-346, miR-376c, | |||||
miR-378, miR-384-5p, miR-494 (2), miR-495, miR-539 | |||||
α6 | GABRA6 | 809 | miR-128, miR-27ab, | NA | N/A |
let7/miR-98 | |||||
β1 | GABRB1 | 407 | miR-30a/30a-5p/30b/30b-5p/ | 428 | miR-103, miR-107, miR-128, miR-143, miR-148b-3p, |
30/384-5p (2), miR-103/107 | miR-152, miR-30a (2) c (2) d (2) e (2), miR-30b-5p (2), | ||||
miR-384-5p (2), miR-411 | |||||
β2 | GABRB2 | 5618 | miR-203,miR-135, miR-218, | 499 | miR-128, miR-199a-5p, miR-203, miR-33, miR-411, miR-485 |
miR-21/590-5p, miR-10, | |||||
miR-101, miR-19, miR-144, | |||||
miR-9 (2), miR-455/455-5p, | |||||
miR-33/33ab | |||||
β3 | GABRB3 | 4060 | miR-26ab/1297, miR-204/211, | 508 | miR-122, miR-186, miR-199a-5p, miR-204, miR-210, miR-211, |
miR-23ab, miR-27ab, miR-218 | miR-23ab, miR-26ab, miR-320, miR-324-5p, miR-329, | ||||
miR-381, miR-539 | |||||
γ1 | GABRG1 | 3428 | 0 | 240 | miR-203, miR-218, miR-379, miR-410, miR-455, miR-488 |
γ2 | GABRG2 | 2106 | miR-150, miR-103/107 | NA | N/A |
γ3 | GABRG3 | 96 | 0 | 114 | miR-15b, miR-16, miR-195, miR-26ab, miR-322, miR-497 |
π | GABRP | 1178 | 0 | NA | N/A |
δ | GABRD | 433 | 0 | 393 | miR-145, miR-19ab, miR-24, miR-328, miR-365 |
ε | GABRE | 1485 | miR-22 | NA | N/A |
θ | GABRQ | 80 | 0 | NA | N/A |
ρ1 | GABRR1 | 464 | 0 | NA | N/A |
ρ2 | GABRR2 | 113 | 0 | 191 | 0 |
ρ3 | GABRR3 | N/A | N/A | 271 | miR-191 |