Figure 3

Structural abundances of NDM-1 based on MBL structural fragment comparisons. (A) Structural abundance, per residue for NDM-1. The first major decrease in abundance at approximately residue 68 corresponds to the mobile flap found in B1 MBLs. The region of structural disagreement starting at about residue 50 and continuing for 30 residues corresponds to the linker region. The last decrease in abundance, at about residues 210-225 align with a lengthy loop region in other MBLs. The flap, anchored linker region and loop L10 are demarcated using the ranges specified in Figure 2.