Figure 1

A 77 year-old female suffered from sequential femoral diaphyseal fractures. (A) The initial femoral fracture happened after 63 months of alendronate therapy. (B) The union was achieved at 5 months by discontinuation of alendronate and administration of bone-forming agent after surgery. (C) She then received a total knee arthroplasty for right knee osteoarthritis 11 months later. However, contralateral femoral fracture was noted 24 months after the initial fracture. (D) After administration of bone-forming agent, bone was healed on 4^th month post-operatively.