Figure 5

Ingenuity pathway gene network analysis of maxillary (upper) vs. mandibular (lower) molar expressed genes. The three most relevant networks identified by Ingenuity Pathway analysis are centered on ERK1/2 (A), and tretinoin (13-cis-retinoic acid, an active retinoid used in therapy) (B). All differentially expressed genes are shown in color, the intensity reflecting the degree of enrichment in mandibular (red) versus maxillary (green) molars. See Legend to Figure 3 for explanations on symbols and types of interactions.