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Table 1 Overview of genes differentially expressed between lower (mandibular) incisor and molar

From: Molars and incisors: show your microarray IDs

A

Genes

Fold change

P-value

Known in teeth

Known as differentially expressed

References

Enriched in molars

Barx1

8.60

3.47E-09

Yes

Yes

[42]

C1qtnf3

7.30

4.37E-08

No

No

 

Adcy8

5.75

2.76E-08

No

No

 

Cntn6

4.91

2.94E-07

No

No

 

Six2

4.82

4.84E-08

Yes

Yes

[43]

Tcfap2b

4.31

1.88E-05

No

No

 

Odz1

4.24

5.02E-09

No

No

 

Vstm2a

4.09

7.28E-08

No

No

 

Nptx1

4.06

1.21E-05

No

No

 

Has2

3.94

1.66E-09

No

No

 

Enriched in incisors

Irx4

-5.31

1.92E-07

No

No

 

Cacna2d3

-5.66

2.55E-08

No

No

 

Mcpt2

-6.39

2.90E-08

No

No

 

Isl1

-6.44

3.53E-08

Yes

Yes

[29]

Alx3

-8.36

6.59E-12

No

No

 

Pax3

-11.72

1.68E-13

Yes

No

[45]

Sfrp4

-12.38

9.88E-10

No

No

 

Hand2

-13.20

6.89E-14

Yes

Yes

[44]

Alx1

-15.95

1.35E-10

No

No

 

Hpse2

-27.41

2.23E-11

No

No

 

B

      

Enriched in molars

Lhx6

3.69

8.95E-08

Yes

Yes

[46]

Sfrp1

3.56

7.94E-06

Yes

No

[47]

Smoc2

3.28

3.28E-08

Yes

Yes

[41]

Shox2

2.85

1.08E-08

Yes

No

[48]

Dlx1

2.81

4.49E-11

Yes

Yes

[17]

Fgf12

2.22

3.32E-06

Yes

No

[49]

Sfrp2

2.16

4.40E-11

No

No

 

Dbx2

1.97

8.51E-06

Yes

No

[50]

Six4

1.95

8.05E-07

Yes

Yes

[43]

Six1

1.83

8.69E-06

Yes

Yes

[43]

Lhx8

1.64

2.87E-06

Yes

No

[51]

Bmpr1a

1.36

7.12E-07

Yes

No

[52]

Mapk1

1.30

3.20E-06

Yes

No

[53]

Enriched in incisors

Gas1

-1.25

6.93E-06

Yes

No

[54]

Hoxa2

-1.41

9.43E-07

Yes

No

[26]

Tlx2

-1.47

7 .35E-07

No

No

 

Irx6

-1.58

3.09E-08

No

No

 

Gdf6

-2.00

4.01E-06

Yes

No

[55]

Aqp1

-2.16

9.51E-08

Yes

No

[56]

Amtn

-2.28

1.65E-08

Yes

Yes

[57]

Prtg

-2.3

9.93E-07

Yes

No

[58]

Slitrk6

-2.37

2.60E-07

Yes

No

[59]

Wnt5a

-2.38

1.38E-05

Yes

No

[60]

Hand1

-2.55

4.01E-06

Yes

Yes

[28]

Prkcq

-2.75

7.17E-07

Yes

No

[61]

Tlx1

-2.84

6.05E-08

Yes

No

[62]

Bmp5

-3.20

3.00E-08

No

No

 

Cyp26c1

-4.05

3.10E-09

Yes

No

[63]

Nts

-4.43

9.56E-10

Yes

No

[64]

Irx4

-5.31

1.92E-07

No

No

 
  1. The table is subdivided in two sections highlighting: (A) The "top ten" genes showing the highest degree of enrichment in incisor (negative values) or molar (positive values); (B) additional examples of differentially expressed genes, some already known from the literature as being expressed in developing teeth, others not predicted from the literature. Separate columns indicate those genes already known as being expressed in developing teeth ("Known in teeth"), and sometimes as being differentially expressed in both tooth types ("Known as differentially expressed"). In all cases, one relevant reference has been selected. For a complete list of differentially expressed genes (with fold changes > 2 or < -2), see Additional file 2.
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BMC Research Notes

ISSN: 1756-0500

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