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Table 2 Patient characteristics

From: Prevalence of gastroduodenal ulcers/erosions in patients taking low-dose aspirin with either 15 mg/day of lansoprazole or 40 mg/day of famotidine: The OITA-GF study 2

 

Group F (n = 31)

Group L (n = 47)

p value

Age (years)

72.0 ± 9.3

74.6 ± 8.8

0.22

Male

26 (83.9%)

32 (68.1%)

0.19

Body mass index (kg/m2)

23.8 ± 3.4

24.3 ± 3.6

0.50

Hypertension

25 (80.6%)

44 (93.6%)

0.14

Diabetes mellitus

9 (29.0%)

18 (38.3%)

0.47

Current smoking

0 (0%)

2 (4.3%)

0.52

Daily alcohol drinking

12 (38.7%)

13 (27.7%)

0.33

Coronary artery disease

26 (83.9%)

43 (91.5%)

0.47

Prior percutaneous coronary intervention

25 (80.6%)

39 (83.0%)

1.0

Prior coronary bypass surgery

1 (3.2%)

2 (4.3%)

1.0

Prior stroke

4 (12.9%)

4 (8.5%)

0.71

Atrial fibrillation

6 (19.4%)

7 (14.9%)

0.76

History of gastroduodenal ulcer

5 (16.1%)

9 (19.1%)

0.77

History of eradication of H. pylori

3 (9.7%)

5 (10.6%)

1.0

Gastrointestinal symptom rating scale

   

  Reflux symptom score

1.4 ± 0.6

1.3 ± 0.6

0.19

  Abdominal pain score

1.4 ± 0.7

1.2 ± 0.5

0.32

  Indigestion score

1.4 ± 0.6

1.6 ± 0.6

0.24

Positive urinary H. pylori antibodies

15 (48.4%)

22 (46.8%)

1.0

Duration of lansoprazole or famotidine treatment

  

0.76

  <1 year

7 (14.9%)

6 (19.4%)

 

  ≥1 year(s)

40 (85.1%)

25 (80.6%)

 

Dose of aspirin

  

1.0

  81 mg/day

1 (3.2%)

2 (4.3%)

 

  100 mg/day

30 (96.8%)

45 (95.7%)

 

Type of aspirin

  

1.0

  Enteric-coated formulation

30 (96.8%)

45 (95.7%)

 

  Buffered formulation

1 (3.2%)

2 (4.3%)

 

Other antiplatelet agents

12 (38.7%)

17 (36.2%)

1.0

Warfarin

8 (25.8%)

8 (17.0%)

0.40

Dabigatran

2 (7.4%)

2 (4.3%)

0.62

Nitrates

10 (32.3%)

16 (34.0%)

1.0

Calcium antagonists

14 (45.2%)

26 (55.3%)

0.49

Angiotensin-converting enzyme inhibitors

3 (9.7%)

4 (8.5%)

1.0

Angiotensin receptor blockers

14 (45.2%)

30 (63.8%)

0.16

Statins

27 (87.1%)

42 (89.4%)

1.0

  1. The data are presented as the mean ± SD or number (%).