Figure 3

Effect of LGG on epithelial cytokine production. Concentrations of IL-6 and IL-8 in culture supernatants of untreated epithelial cells (epithelial) or epithelial cells incubated with pneumococci (Pnc), pneumococci with 100 U/ml heparin (Heparin); or~5 × 106 CFU LGG (LGG low), or ~5 × 107 CFU LGG (LGG high) added one hour prior to the addition of pneumococcal isolates PMP843 (serotype 19 F) (A and C) and PMP6 (serotype 5) (B and D) in the adherence assay. Data reported as mean + SD (n=3).