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Table 2 Characteristics of HCC and comparison of tumor characteristics among viral-HCC vs. viral marker negative HCC

From: Hepatocellular carcinoma in Native South Asian Pakistani population; trends, clinico-pathological characteristics & differences in viral marker negative & viral-hepatocellular carcinoma

  ALL HCC cases Comparison of viral-HCC vs. viral marker negative HCC
  n = (645)    
  Mean ± SD/n (%) Viral HCC (n = 546) Viral marker negative HCC(n = 99) P value
Duration between diagnosis of cirrhosis & HCC(months)     
  00 291(45.1) 226(41.4) 65(65.7) <0.001
  1-55 243(37.7) 219(40.1) 24(24.2)  
  >55 111(17.2) 101(18.5) 10(10.1)  
Mode of diagnosis     
  On screening 53(8.2) 52(9.5) 1(1.0) 0.001
  Incidental 57(8.8) 44(8.1) 13(13.1)  
  Symptomatic 535(82.9) 450(82.4) 85(85.9)  
Stage of HCC     
  Non-advance 240(37.2%) 222(40.7) 18(18.2) <0.001
  Advance 405(62.8%) 324(59.3) 81(81.8)  
Macroscopic types     
  Solitary 246(38.1) 213(39.0) 33(33.3) 0.04
  Paucifical (≤ 3 nodules) 259(40.2) 223(40.8) 36(36.4)  
  Multifocal(>3 nodules) 96(14.9) 79(14.5) 17(17.2)  
  Massive/infiltrative 44(6.8%) 31(5.7) 13(13.1)  
Maximum tumor size (cm)     
  < 5 359(55.65) 326(59.7) 33(33.3) <0.001
  5-10 213(33.02) 173(31.7) 40(40.4)  
  >10 73(11.31) 47(8.6) 26(26.3)  
Hepatic lobes     
  Left 81(12.6) 69(12.6) 12(12.1) 0.98
  Right 387(60) 327(59.9) 60(60.6)  
  Both 177(27.4) 150(27.5) 27(27.3)  
PVT     
  No 429(66.5) 359(65.8) 70(70.7) 0.33
  Yes 216(33.5) 187(34.2) 29(29.3)  
Extra hepatic spread     
  No 560(86.8) 479(87.7) 81(81.8) 0.12
  Yes 85(13.2) 67(12.3) 18(18.2)