Table 2 Characteristics of HCC and comparison of tumor characteristics among viral-HCC vs. viral marker negative HCC
| Â | ALL HCC cases | Comparison of viral-HCC vs. viral marker negative HCC | ||
|---|---|---|---|---|
|  | n = (645) |  |  |  |
|  | Mean ± SD/n (%) | Viral HCC (n = 546) | Viral marker negative HCC(n = 99) | P value |
Duration between diagnosis of cirrhosis & HCC(months) | Â | Â | Â | Â |
  00 | 291(45.1) | 226(41.4) | 65(65.7) | <0.001 |
  1-55 | 243(37.7) | 219(40.1) | 24(24.2) |  |
  >55 | 111(17.2) | 101(18.5) | 10(10.1) |  |
Mode of diagnosis | Â | Â | Â | Â |
  On screening | 53(8.2) | 52(9.5) | 1(1.0) | 0.001 |
  Incidental | 57(8.8) | 44(8.1) | 13(13.1) |  |
  Symptomatic | 535(82.9) | 450(82.4) | 85(85.9) |  |
Stage of HCC | Â | Â | Â | Â |
  Non-advance | 240(37.2%) | 222(40.7) | 18(18.2) | <0.001 |
  Advance | 405(62.8%) | 324(59.3) | 81(81.8) |  |
Macroscopic types | Â | Â | Â | Â |
  Solitary | 246(38.1) | 213(39.0) | 33(33.3) | 0.04 |
  Paucifical (≤ 3 nodules) | 259(40.2) | 223(40.8) | 36(36.4) |  |
  Multifocal(>3 nodules) | 96(14.9) | 79(14.5) | 17(17.2) |  |
  Massive/infiltrative | 44(6.8%) | 31(5.7) | 13(13.1) |  |
Maximum tumor size (cm) | Â | Â | Â | Â |
  < 5 | 359(55.65) | 326(59.7) | 33(33.3) | <0.001 |
  5-10 | 213(33.02) | 173(31.7) | 40(40.4) |  |
  >10 | 73(11.31) | 47(8.6) | 26(26.3) |  |
Hepatic lobes | Â | Â | Â | Â |
  Left | 81(12.6) | 69(12.6) | 12(12.1) | 0.98 |
  Right | 387(60) | 327(59.9) | 60(60.6) |  |
  Both | 177(27.4) | 150(27.5) | 27(27.3) |  |
PVT | Â | Â | Â | Â |
  No | 429(66.5) | 359(65.8) | 70(70.7) | 0.33 |
  Yes | 216(33.5) | 187(34.2) | 29(29.3) |  |
Extra hepatic spread | Â | Â | Â | Â |
  No | 560(86.8) | 479(87.7) | 81(81.8) | 0.12 |
  Yes | 85(13.2) | 67(12.3) | 18(18.2) |  |