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Table 5 Comparison of viral marker negative HCC with HCV-HCC, HBV-HCC, combination-HCC

From: Hepatocellular carcinoma in Native South Asian Pakistani population; trends, clinico-pathological characteristics & differences in viral marker negative & viral-hepatocellular carcinoma

 

Percentages

Unadjusted OR(95% CI)

Adjusted OR(95% CI)

Variable

HCV

HBV

Combination

NBN

HBV

Combination

NBNC

HBV

NBNC

Combination

Gender

          

  Female

35.6

17.6

17.9

25.3

1

  

1

  

  Male

64.4

82.4

82.1

74.7

2.5 (1.5-4.3)

2.5 (1.2-5.1)

1.6 (0.9-2.6)

2.3 (1.3-3.8)

1.5 (0.8-2.5)

2.6 (1.2-5.3)

Diagnosis of HCC

          

  On screening

11.9

2.5

1.9

1.0

1

  

1

  

  incidental

8.1

9.2

5.4

13.1

5.3 (1.3-20.9)

0.88 (0.19-3.96)

19.06 (2.3-153.5)

3.4 (0.8-13.9)

10.1 (1.2-84.7)

0.8 (0.17-3.8)

  symptomatic

80.1

88.2

85.7

85.9

5.1 (1.5-17.0)

1.4 (0.53-3.76)

12.5 (1.7-92.7)

4.1 (1.2-13.9)

8.1 (1.1-60.3)

1.4 (0.5-3.9)

BMI (Kg/m 2 )

          

  18-22.9

26.7

35.3

26.8

25.3

1

  

1

  

  <18

3.8

11.8

3.6

10.1

2.3 (1.03-2.37)

0.94 (0.19-4.56)

2.8 (1.12-7.11)

2.8 (1.2-6.6)

3.1 (1.1-8.3)

1.1 (0.2-5.0)

  23-24.9

22.9

21.0

26.8

27.3

0.69 (0.39-1.23)

1.16 (0.53-2.52)

1.25 (0.53-2.52)

0.7 (0.3-1.3)

1.3 (0.6-2.4)

1.1 (0.5-2.4)

  ≥ 25

46.6

31.9

42.9

37.4

0.51 (0.31-0.85)

0.91 (0.45-1.82)

0.84 (0.48-1.48)

0.6 (0.3-1.1)

0.9 (0.5-1.7)

1.0 (0.5-2.0)

Maximum diameter (cm)

          

  <5

62.5

49.6

62.5

33.3

1

  

1

  

  5-10

29.1

39.5

32.1

40.5

1.7 (1.09-2.6)

1.1 (0.59-2.0)

2.6 (1.5-4.3)

1.5 (0.9-2.5)

2.3 (1.3-4.0)

0.9 (0.5-1.7)

  >10

8.4

10.9

5.4

26.3

1.64 (0.8-3.3)

0.64 (0.18-2.2)

5.8 (3.1-11.1)

1.0 (0.5-2.2)

4.0 (2.0-7.9)

0.5 (0.1-1.7)

Duration between diagnosis of CLD and HCC

  >55

22.1

6.7

19.6

10.1

1

  

1

  

  zero

37.5

52.1

44.6

65.7

4.5 (2.0-10.0)

1.3 (0.62-2.8)

3.8 (1.8-7.8)

3.7 (1.6-8.4)

3.0 (1.4-6.5)

1.1 (0.4-2.4)

  1-55

40.4

41.2

35.7

24.2

3.3 (1.5-7.4)

0.9 (0.4-2.1)

1.3 (0.5-2.8)

2.6 (1.1-6.1)

1.2 (0.5-2.8)

0.7 (0.3-1.7)

Diabetes

          

  No

55.8

72.3

78.6

49.5

1

  

1

  

  Yes

44.2

27.7

21.4

50.5

0.48 (0.30-0.76)

0.34 (0.17-0.67)

1.2 (0.8-2.0)

0.5 (0.3-0.9)

1.6 (0.1-2.5)

0.3 (0.2-0.6)

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BMC Research Notes

ISSN: 1756-0500

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