Skip to main content

Table 1 Set of knockouts and the corresponding chemical reactions used as case study

From: TNA4OptFlux – a software tool for the analysis of strain optimization strategies

Reaction Stoichiometric equation
Serine hydroxymethyltransferase L-serine + tetrahydrofolate < = > glycine + 5,10-methylenetetrahydrofolate + H2O
pyridine nucleotide transhydrogenase H+e + NADH + NADP+ = > H+c + NAD+ + NADPH
Succinate dehydrogenase FAD+ + Succinate = > FADH2 + Fumarate
Transketolase I D-erythrose-4-phosphate + D-xylulose-5-phosphate < = > D-fructose-6-phosphate + D-glyceraldehyde-3-phosphate