Table 4 Patient characteristics - hip
From: Tranexamic acid and the reduction of blood loss in total knee and hip arthroplasty: a meta-analysis
Study, Year | Number of patients TXA/C | Gender distribution % male TXA /C | Mean age TXA,C (SD or range) | Mean weight (kg) – TXA, C (SD or Range) | TBL – TXA,C (mL) (SD) | P Value | Patient requiring allogeneic transfusions (TXA, C) | P Value | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
TXA | C | TXA | C | TXA | C | TXA | C | TXA | C | TXA | C | |||
Ekbäck, 2000[28] | 20 | 20 | 45 | 55 | 66.4 (9.0) | 65.6 (8.8) | 81.1 (13) | 76.8 (13) | 1130 (400) | 1770 (523) | <0.001 | 5 | 5 | N/R |
Benoni, 2000[29] | 20 | 19 | 30 | 58 | 69.5 (10) | 68 (10) | 76 (14), | 77 (11) | 990 â—Š(210 ), | 950 â—Š(162.5) | N/R | 45 | 79 | 0.05 |
Benoni, 2001[33] | 18 | 20 | 50 | 50 | 66 (9.5) | 68 (9.4) | 79 (16) | 78 (17) | 759 (275.8†) | 996 (398†) | 0.03 | 22 | 40 | 0.2 |
Husted, 2003[25] | 20 | 20 | 35 | 30 | 65 | 67 | N/R | 814 (1323.8†) | 1231 (1692.7†) | 0.001 | 10 | 35 | 0.04 | |
Yamasaki, 2004[41] | 20 | 20 | 95 | 90 | 55.5 (14.2) | 61.2 (6.9) | 52.6 (11.5) | 54.5 (8.7) | 1350 (477) | 1667 (401) | <0.05 | 0 | 0 | N/R |
Garneti, 2004[14] | 25 | 25 | N/R | 69.6 (11.99) | 67.6 (11.4) | N/R | 1443 (809) | 1340 (665) | 0.822 | 64 | 56 | N/R | ||
Lemay, 2004[34] | 20 | 19 | 60 | 68 | 59.7 (10.3) | 53.6 (12.8) | 80.1 (15.7) | 74.7 (14.1) | 1308 (462) | 1469 (405) | N/R | 0 | 42 | 0.0012 |
Johansson, 2005[26] | 47 | 53 | 53 | 53 | 69 (7) | 69 (7) | 81 (16) | 78 (13) | 969 (434) | 1324 (577) | <0.001 | 17 | 43 | 0.009 |
Niskanen, 2005[30] | 19 | 20 | 32 | 35 | 66 (9.1) | 65 (8.2) | 80 (19) | 82 (14) | 792 (390.1†) | 1102 (485.2 †) | 0.03 | 26 | 40 | 0.3 |
Claeys, 2007[32] | 20 | 20 | 25 | 35 | 73 (8) | 68 (11) | 76 (15) | 72 (16) | 801 (244) | 1038 (289) | 0.013 | 5 | 30 | <0.05 |
Kazemi, 2010[8] | 32 | 32 | 72 | 63 | 46.6 (16.2) | 45.4 (17.2) | 72.1 (10.4), | 69.9 (11.1) | 1024 (544) | 1399 (587) | 0.024 | N/R | N/R | |
Malhotra, 2011[20] | 25 | 25 | 40 | 48 | 52.6 (39–72) | 54.7 (40–71) | 80.2 (58–100) | 81.9 (62–98) | 410 (300–510) – range | 615 (515–750) –range | <0.5 | 24 | 72 | N/R |
McConnell, 2011[38] | 22 | 22 | 32 | 41 | N/R | N/R | N/R | N/R | 930 (399†) | 1200 (469†) | 0.02 | 0 | 0 | N/R |
Imai, 2012[39] * | 24, 20, 25, 26 | 22 | 17, 20, 16, 15 | 23 | 64.4 (49–74), 62.2 (50–85), 63.3 (47–80), 63.3 (48–81) | 60.2 (54–72) | 55.9 (44–86), 54.1 (40–76), 54.1 (41–70), 53.8 (44–73) | 56.3 (47–80) | 649, 566, 388, 418** | 1026** | N/R | 0 | 0 | N/R |