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Table 4 Comprehensive behavioral test battery of Grin1Rgsc174/Grin1+mice

From: ENU-mutagenesis mice with a non-synonymous mutation in Grin1 exhibit abnormal anxiety-like behaviors, impaired fear memory, and decreased acoustic startle response

Test

Age (w)

Number of samples

Figure/Table

Light–dark transition test

10

C, 11; M, 10

Figure 3

Open field test

10

C, 11; M, 10

Figure 2

Hot plate test

11

C, 11; M, 10

Figure 1

Elevated plus maze test

11

C, 11; M, 9

Figure 3

General health test

12

C, 11; M, 10

Figure 1

Social interaction test in novel environment

12

C, 5; M, 3*

Figure 4

Rotarod test

12

C, 11; M, 10

Figure 1

Crawley’s three-chamber social approach test

12-13

C, 11; M, 10

Figure 4

Acoustic startle response test

14

C, 11; M, 10

Figure 7

Prepulse inhibition test

14

C, 10; M, 7

Table 2

Porsolt forced swim test

15

C, 11; M, 10

Figure 5

Gait analysis

27-28

C, 10; M, 7

Figure 1

Eight-arm radial maze test

37-40

C, 10; M, 7

Figure 6

Contextual and cued fear conditioning Test

46

C, 11; M, 10

Figure 6

Tail suspension test

46

C, 11; M, 10

Table 2

Social interaction test in familiar environment

48-49

C, 5; M, 3*

Figure 4

  1. C: Controls.
  2. M: Mutants.
  3. * Number of pairs.