Table 2 Exclusively-viral functions identified by DASH in the HHV-8 genome
From: Domain analysis of symbionts and hosts (DASH) in a genome-wide survey of pathogenic human viruses
Gene | Protein gi | E-value | Dom. Cov. | Function | PfamA accession | Function type | Reference |
|---|---|---|---|---|---|---|---|
ORF25 | 139472823 | 0.0 | 1.00 | Herpes virus major capsid protein | PF03122 | S/M | Russo et al. |
ORF44 | 139472836 | 0.0 | 1.00 | Helicase | PF02689 | S/M | Russo et al. |
ORF6 | 139472807 | 0.0 | 0.98 | ssDNA binding protein | PF00747 | S/M | Russo et al. |
ORF8 | 139472808 | 5.6e-272 | 0.99 | Glycoprotein B | PF00606 | S/M | Russo et al. |
ORF63 | 139472855 | 1.4e-271 | 1.00 | Herpes virus tegument protein U30 | PF04523 | S/M | Russo et al. |
K15 | 139472806 | 1.2e-258 | 1.00 | Herpesvirus Latent membrane protein 2 | PF06126 | S/M | Choi et al. |
ORF24 | 139472822 | 2.6e-208 | 1.00 | Herpesvirus UL87 family | PF03043 | C | DASH |
ORF43 | 139472835 | 1.1e-200 | 1.00 | Herpesvirus UL6 like | PF01763 | C | DASH |
ORF22 | 139472821 | 9.1e-197 | 1.00 | Herpesvirus glycoprotein H | PF02489 | S/M | Russo et al. |
ORF50 | 139472840 | 1.9e-193 | 1.00 | Transcription activation factor (transactivator) | PF03326 | S/M | Russo et al. |
ORF7 | 139472861 | 7.5e-193 | 1.00 | Herpesvirus processing and transport protein | PF01366 | S/M | Russo et al. |
ORF19 | 139472819 | 7.2e-182 | 1.00 | Herpesvirus UL25 family | PF01499 | C | DASH |
K8 | 139472841 | 1.3e-170 | 1.00 | Transcriptional activator | PF07188 | S/M | Wu et al. |
ORF37 | 139472831 | 3.0e-164 | 0.99 | Alkaline exonuclease | PF01771 | S/M | Russo et al. |
ORF29 | 139472824 | 1.1e-154 | 1.00 | Probable DNA packing protein | PF02499, PF02500 | S/M | Russo et al. |
ORF59 | 139472852 | 2.2e-139 | 1.00 | Herpes DNA replication accessory factor | PF04929 | S/M | Russo et al. |
ORF39 | 139472832 | 6.3e-136 | 0.96 | Herpesvirus glycoprotein M | PF01528 | S/M | Russo et al. |
ORF68 | 139472883 | 7.6e-133 | 0.99 | Herpesvirus putative major envelope glycoprotein | PF01673 | S/M | Russo et al. |
ORF58 | 139472879 | 5.2e-128 | 1.00 | Herpesvirus BMRF2 protein | PF04633 | S/M | Russo et al. |
ORF49 | 139472877 | 3.3e-108 | 1.00 | BRRF1-like protein | PF04793 | S/M | Russo et al. |
ORF34 | 139472829 | 1.6e-106 | 0.99 | UL95 family | PF03038 | C | DASH |
ORF26 | 139472871 | 3.1e-103 | 1.00 | Herpesvirus VP23 like capsid protein | PF01802 | S/M | Russo et al. |
ORF18 | 139472818 | 8.6e-99 | 1.00 | UL79 family | PF03049 | C | DASH |
ORF23 | 139472870 | 1.1e-98 | 1.00 | Herpesvirus BTRF1 protein conserved region | PF04682 | C | DASH |
ORF10 | 139472862 | 6.3e-94 | 0.99 | Herpesvirus dUTPase protein | PF04797 | S/M | McGeehan et al., Davidson et al. |
ORF11 | 139472810 | 5.2e-93 | 0.99 | Herpesvirus dUTPase protein | PF04797 | S/M | McGeehan et al., Davidson et al. |
ORF69 | 139472884 | 3.5e-91 | 0.97 | Herpesvirus UL31-like protein | PF02718 | C | DASH |
ORF55 | 139472846 | 3.9e-90 | 0.96 | Herpes virus U44 protein | PF04533 | C | DASH |
ORF32 | 139472827 | 4.2e-84 | 1.00 | Herpesvirus UL17 protein | PF04559 | C | DASH |
ORF66 | 139472857 | 3.9e-82 | 0.99 | UL49 family | PF03117 | C | DASH |
ORF62 | 139472854 | 4.7e-81 | 1.00 | Herpesvirus capsid shell protein VP19C | PF03327 | S/M | Russo et al. |
ORF48 | 139472839 | 4.4e-78 | 1.00 | Herpesvirus protein of unknown function | PF05734 | C | DASH |
ORF17 | 139472867 | 2.2e-77 | 0.65 | Assemblin (Peptidase family S21) | PF00716 | S/M | Unal et al. |
ORF31 | 139472825 | 8.0e-71 | 0.98 | UL92 family | PF03048 | C | DASH |
K1 | 139472859 | 1.5e-69 | 1.00 | Glycoprotein | PF02960, PF11049 | S/M | Lee et al. |
ORF67 | 139472856 | 1.7e-69 | 0.97 | Herpesvirus virion protein U34 | PF04541 | C | DASH |
ORF33 | 139472828 | 2.4e-69 | 0.99 | Herpesvirus UL16/UL94 family | PF03044 | C | DASH |
ORF64 | 139472881 | 1.3e-61 | 1.00 | Herpesvirus tegument protein | PF04843 | S/M | Russo et al. |
ORF20 | 139472820 | 2.1e-61 | 0.99 | Herpes virus protein UL24 | PF01646 | C | DASH |
ORF65 | 139472858 | 2.2e-59 | 1.00 | Gammaherpesvirus capsid protein | PF06112 | S/M | Russo et al. |
ORF42 | 139472834 | 5.3e-56 | 1.00 | Herpesvirus UL7 like | PF01677 | C | DASH |
ORF57 | 139472848 | 1.4e-54 | 0.99 | Herpesvirus transcriptional regulator | PF05459 | S/M | Kirshner et al. |
ORF35 | 139472830 | 1.6e-47 | 0.99 | Gammaherpesvirus protein of unknown function | PF05852 | C | DASH |
ORF40 | 139472833 | 4.2e-46 | 1.00 | DNA helicase/primase | PF05774, PF03324 | S/M | Russo et al. |
ORF47 | 139472876 | 6.3e-36 | 0.95 | Viral glycoprotein L | PF11108 | S/M | Russo et al. |
ORF52 | 139472843 | 5.1e-35 | 1.00 | Herpesvirus BLRF2 protein | PF05812 | S/M | Russo et al. |
ORF53 | 139472844 | 1.7e-28 | 0.99 | UL73 viral envelope glycoprotein | PF03554 | C | DASH |