Figure 1

Performance of the HB-F fibrosis score in the training cohort of patients. (A) The ranges of HB-F scores in patients with different ISHAK fibrosis score (FS1-FS6). Gray boxes represented the 25%-75% quartiles; The middle horizontal lines represented the median scores. (B) The ranges of HB-F scores in subjects stratified by FS < 5 (non-cirrhotic patients) and FS > =5 (cirrhosis) (P < 0.001). (C) The ranges of HB-F scores in subjects grouped by FS < 4 and FS > =4 (prominent fibrosis) (P < 0.001). (D) The ROC curve of the HB-F score for the diagnosis of cirrhosis patients (AUC = 0.799). (E) The ROC curve for the diagnosis of prominent fibrosis patients (AUC = 0.810).