|
Age at biopsy in years, mean ± SD
|
44.4 ± 11.8
|
45.6 ± 11.4
|
|
Male, n (%)
|
179 (84)
|
175 (83)
|
|
Biopsy
| | |
|
Necroinflammation score, mean ± SD
|
|
Periportal inflammation
|
1.0 ± 0.8
|
0.9 ± 0.8
|
|
Confluence necrosis
|
0.3 ± 1.0
|
0.2 ± 0.8
|
|
Focal inflammation
|
1.9 ± 0.7
|
2.0 ± 0.7
|
|
Portal inflammation
|
2.2 ± 1.0
|
2.2 ± 0.9
|
|
ISHAK fibrosis score, n (%)
| | |
|
0
|
1 (1)
|
1 (1)
|
|
1
|
28 (13)
|
28 (13)
|
|
2
|
32 (15)
|
32 (15)
|
|
3
|
70 (33)
|
71 (34)
|
|
4
|
21 (10)
|
21 (10)
|
|
5
|
46 (22)
|
45 (21)
|
|
6
|
15 (7)
|
13 (6)
|
|
HBeAg-positive, n (%)
|
109 (51)
|
91 (43)
|
|
Biochemistry, mean ± SD
| | |
|
AST (IU/mL)
|
91.3 ± 83.6
|
94.9 ± 100.1
|
|
ALT (IU/mL)
|
170.1 ± 173.8
|
166.2 ± 177.9
|
|
AST/ALT
|
0.6 ± 0.3
|
0.6 ± 0.3
|
|
AFP (ng/mL)
|
10.5 ± 22.2
|
20.4 ± 82.0
|
|
Bilirubin (mg/dL)
|
1.0 ± 0.7
|
1.0 ± 0.4
|
|
GGT (IU/L)
|
69.0 ± 77.0
|
60.1 ± 57.3
|
|
Albumin (g/dL)
|
4.6 ± 0.3
|
4.5 ± 0.4
|
|
Platelet (×103/mm3)
|
188.2 ± 54.2
|
189.2 ± 49.4
|
|
Prothrombin time prolongation (sec)
|
1.0 ± 0.6
|
1.0 ± 0.8
|
|
White blood cell (×103/mm3)
|
5.7 ± 1.7
|
5.5 ± 1.6
|
|
Hemoglobin (g/dL)
|
15.1 ± 1.4
|
15.2 ± 1.3
|
|
Alpha-1 globulin (g/dL)
|
0.2 ± 0.1
|
0.2 ± 0.0
|
|
Alpha-2 globulin (g/dL)
|
0.8 ± 0.2
|
0.8 ± 0.1
|
|
Beta globulin (g/dL)
|
0.8 ± 0.1
|
0.7 ± 0.1
|
|
Gamma globulin (g/dL)
|
1.5 ± 0.4
|
1.4 ± 0.4
|
|
Albumin/Globulin
|
1.5 ± 0.3
|
1.5 ± 0.3
|
