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Table 2 Univariate and multivariate analysis for factors associated with liver fibrosis

From: Development of a non-invasive fibrosis test for chronic hepatitis B patients and comparison with other unpatented scores

Characteristics Beta (95% CI) P Adjusted beta (95% CI) P
Age at biopsy 0.035 (0.018, 0.052) < 0.001 0.018 (0.001, 0.036) 0.044
Male 0.046 (-0.597, 0.506) 0.870   
HBeAg-positive -0.496 (-0.943, -0.048) 0.030   
AST (IU/mL) 0.001 (-0.001, 0.004) 0.363   
ALT (IU/mL) 0.000 (-0.001, 0.001) 0.802   
AST/ALT 1.881 (1.199, 2.563) < 0.001 1.085 (0.368, 1.803) 0.003
AFP (ng/mL) 0.012 (0.001, 0.023) 0.026   
Bilirubin (mg/dL) 0.142 (-0.168, 0.452) 0.367   
GGT (IU/L) 0.006 (0.002, 0.009) 0.003   
Albumin (g/dL) -1.440 (-2.839, -0.042) 0.044   
Platelet (×103/mm3) -0.012 (-0.015, -0.009) < 0.001 -0.009 (-0.013, -0.005) < 0.001
Prothrombin time prolongation (sec) 0.781 (0.404, 1.157) < 0.001 0.449 (0.098, 0.800) 0.012
White blood cell (×103/mm3) 0.049 (-0.093, 0.192) 0.495   
Hemoglobin (g/dL) 0.053 (-0.125, 0.231) 0.558   
Alpha-1 globulin (g/dL) -0.898 (-2.683, 0.886) 0.322   
Alpha-2 globulin (g/dL) -0.505 (-1.746, 0.736) 0.423   
Beta globulin (g/dL) -0.808 (-2.160, 0.545) 0.240   
Gamma globulin (g/dL) 0.214 (-0.327, 0.754) 0.436   
Albumin/Globulin -0.422 (-1.180, 0.335) 0.273