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Table 3 Performance of six fibrosis score for evaluation of liver fibrosis and cirrhosis in patients with chronic hepatitis B

From: Development of a non-invasive fibrosis test for chronic hepatitis B patients and comparison with other unpatented scores

Non-invasive index AUC (95% CI) Difference between areas (95% CI)* P*
Prominent fibrosis    
HB-F (training) 0.810 (0.751, 0.861)   
HB-F (verification) 0.797 (0.737, 0.849)   
FIB-4 0.772 (0.709, 0.826) 0.0255 (-0.0236, 0.0746) 0.3087
Fibroindex 0.767 (0.704, 0.822) 0.0301 (-0.0298, 0.0899) 0.3251
ARPI 0.753 (0.689, 0.810) 0.0439 (-0.0302, 0.1180) 0.2454
AAR 0.630 (0.561, 0.696) 0.1670 (0.0947, 0.2390) < 0.0001
FI 0.724 (0.659, 0.784) 0.0728 (0.0093, 0.1360) 0.0246
Cirrhosis    
HB-F (training) 0.799 (0.739, 0.851)   
HB-F (verification) 0.757 (0.694, 0813)   
FIB-4 0.727 (0.662, 0.786) 0.0297 (-0.0223, 0.0818) 0.2624
Fibroindex 0.722 (0.656, 0.781) 0.0351 (-0.0320, 0.1020) 0.3054
ARPI 0.698 (0.631, 0.759) 0.0589 (-0.0244, 0.1400) 0.1556
AAR 0.636 (0.568, 0.701) 0.1210 (0.0470, 0.1950) 0.0013
FI 0.717 (0.651, 0.777) 0.0403 (-0.0283, 0.1090) 0.2497
  1. *Comparison between the AUC of HB-F (verification cohort) and those of the other scoring methods.