Representative photomicrographies of immunohistochemical detection of CD3+and CD79α+lymphocytes within the nervous tissue of dogs (LTN group). a: CD3+ T lymphocytes in the leptomeninges (arrow) from the temporal cortex as the major component of the inflammatory infiltrate. b: Disperse CD3+ T lymphocytes in the choroid plexus (arrowhead) and in the sub-ependymal area (arrow). c: Inflammatory infiltrate composed of CD3+ T lymphocytes (arrow) in the lateral ventricular ependyma. Note that the immunostained cells are just under the ciliated cells monolayer (arrowhead) that forms the ependyma. d: Perivascular cuff constituted mainly by CD3+ T lymphocytes (arrow) in the thalamus. e: Presence of two CD79α+ B cells (arrow) in the subependymal area. f: Few CD79α+ B cells (arrow) in the same perivascular cuff in the thalamus shown in d. Streptavidin–biotin peroxidase complex method. Scale bar = 50 μm.