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Table 4 Clinical outcomes 0-48 months

From: Long-term outcomes of anthroposophic treatment for chronic disease: a four-year follow-up analysis of 1510 patients from a prospective observational study in routine outpatient settings

Outcome (range)

Age years

N

0 months

48 months

0-48 month difference*

SRM

Mean (95%-CI)

Mean (95%-CI)

Mean (95%-CI)

P-value

All diagnoses

Symptom Score (0-10)

-All patients

1-75

1501

6.09 (6.00-6.18)

3.26 (3.14-3.37)

2.83 (2.71-2.96)

<0.001

1.13

-Adults

17-75

1067

6.07 (5.96-6.17)

3.41 (3.27-3.54)

2.66 (2.51-2.81)

<0.001

1.09

-Children

1-16

434

6.15 (5.98-6.32)

2.90 (2.68-3.11)

3.25 (3.01-3.50)

<0.001

1.25

-Art therapy

1-75

273

6.19 (6.00-6.38)

3.24 (2.98-3.50)

2.95 (2.68-3.23)

<0.001

1.28

-Eurythmy therapy

1-75

791

6.23 (6.10-6.36)

3.35 (3.18-3.51)

2.88 (2.70-3.06)

<0.001

1.12

-Rhythmical massage Therapy

1-75

146

6.06 (5.78-6.33)

3.56 (3.16-3.96)

2.50 (2.08-2.91)

<0.001

0.98

-Medical therapy

1-75

291

5.63 (5.43-5.84)

2.88 (2.62-3.14)

2.75 (2.47-3.04)

<0.001

1.12

First ranked symptom (0-10)

1-75

1491

6.42 (6.32-6.52)

3.29 (3.29-3.42)

3.13 (2.99-3.28)

<0.001

1.09

CES-D (0-60)

17-75

849

21.83 (21.02-22.64)

15.34 (14.55-16.13)

6.49 (5.72-7.27)

<0.001

0.56

SF-36 Physical Component

17-75

1043

42.98 (42.33-43.68)

46.67 (46.01-47.33)

3.69 (3.11-4.27)

<0.001

0.39

SF-36 Mental Component

17-75

1043

37.90 (37.14-38.66)

45.41 (44.69-46.13)

7.51 (6.75-8.26)

<0.001

0.60

SF-36 scales (0-100)

-Physical Function

17-75

1069

74.70 (73.28-76.13)

80.30 (78.84-81.76)

5.60 (4.38-6.82)

<0.001

0.28

-Role Physical

17-75

1063

44.75 (42.38-47.12)

66.35 (63.95-68.74)

21.60 (19.03-24.17)

<0.001

0.51

-Role Emotional

17-75

1059

49.32 (46.79-51.86)

70.46 (68.08-72.84)

21.14 (18.44-23.84)

<0.001

0.47

-Social Functioning

17-75

1072

59.17 (57.57-60.76)

74.95 (73.43-76.47)

15.79 (14.12-17.46)

<0.001

0.57

-Mental Health

17-75

1070

53.62 (52.44-54.80)

65.32 (64.12-66.52)

11.70 (10.54-12.86)

<0.001

0.60

-Bodily Pain

17-75

1070

54.19 (52.47-55.91)

67.70 (66.01-69.38)

13.51 (11.84-15.17)

<0.001

0.49

-Vitality

17-75

1070

38.05 (36.93-39.18)

51.72 (50.48-52.97)

13.67 (12.41-14.92)

<0.001

0.65

-General Health

17-75

1061

50.22 (49.04-51.39)

59.12 (57.80-60.45)

8.91 (7.76-10.06)

<0.001

0.47

Diagnosis groups

ADHD: FBB-HKS Total (0-3)

3-16

60

1.74 (1.61-1.87)

1.25 (1.08-1.41)

0.49 (0.34-0.64)

<0.001

0.85

Anxiety Severity (0-10)

17-75

61

7.08 (6.61-7.55)

3.72 (2.99-4.45)

3.36 (2.67-4.06)

<0.001

1.24

Asthma Severity (0-10)

2-70

88

5.50 (5.04-5.96)

3.11 (2.59-3.64)

2.39 (1.86-2.91)

<0.001

0.96

Migraine Severity (0-10)

17-75

44

6.77 (6.23-7.32)

4.18 (3.34-5.02)

2.59 (1.84-3.34)

<0.001

1.05

Depression: CES-D (0-60)

17-70

133

34.93 (33.58-36.27)

19.75 (17.58-21.92)

15.18 (12.94-17.41)

<0.001

1.16

Low back pain: HFAQ (0-100)

17-75

73

62.13 (57.54-66.72)

75.71 (71.48-79.95

13.59 (9.83-17.34)

<0.001

0.84

Low back pain: LBPRS (0-100)

17-75

72

36.61 (32.75-40.46)

27.69 (23.37-32.01)

8.92 (5.11-12.73)

<0.001

0.55

  1. Patients with available baseline values, last value carried forward. CI Confidence interval. *Positive differences indicate improvement. SRM Standardised Response Mean effect size (minimal: < 0.20, small: 0.20-0.49, medium: 0.50-0.79, large: ≥0.80). CES-D Center for Epidemiological Studies Depression Scale, German version [34, 35], ADHD Attention Deficit Hyperactivity Symptoms, FBB-HKS Total Fremdbeurteilungsbogen für Hyperkinetische Störungen (parents’ questionnaire for ADHD core symptoms), Total score [53, 54]), HFAQ Hanover Functional Ability Questionnaire [51], LBPRS Low Back Pain Rating Scale Pain Score [52].