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Table 1 Growth responses of S . cerevisiae , E . coli , S . aureus and P . aeruginosa to I 2 and H 2 O 2 combined at various concentrations in liquid growth media

From: Co-operative inhibitory effects of hydrogen peroxide and iodine against bacterial and yeast species

S. cerevisiae
I2 \H2O2* 0 μM 1 mM 1.5 mM 2 mM 2.5 mM 3 mM 4 mM
0 μM +++ +++ +++ +++ +++ +++ -
20 μM +++ +++ +++ +++ +++ +++ -
25 μM +++ +++ +++ +++ +++ ++ -
50 μM +++ +++ +++ +++ +++ + -
75 μM +++ +++ +++ +++ +++ 1 -
100 μM +++ +++ +++ +++ 0.95 - -
150 μM +++ +++ +++ +++ - - -
200 μM +++ +++ ++ 1.16 - - -
250 μM +++ +++ ++ 1.33 - - -
300 μM - - - - - - -
E . coli
I2 \H2O2 0 μM 100 μM 200 μM 400 μM 600 μM 800 μM 1 mM
0 μM +++ +++ +++ +++ +++ - -
50 μM +++ +++ +++ 0.58 - - -
100 μM +++ +++ +++ - - - -
200 μM +++ +++ ++ - - - -
300 μM +++ +++ 0.75 - - - -
400 μM +++ 0.79 - - - - -
500 μM - - - - - - -
S . aureus
I2 \H2O2 0 μM 75 μM 100 μM 150 μM 200 μM 300 μM 400 μM
0 μM +++ +++ +++ +++ - - -
100 μM +++ +++ +++ 1 - - -
150 μM +++ +++ +++ - - - -
200 μM +++ ++ 1 - - - -
250 μM +++ 1 - - - - -
300 μM +++ - - - - - -
400 μM - - - - - - -
P . aeruginosa
I2 \H2O2 0 mM 1 mM 1.5 mM 2 mM 2.5 mM 3 mM 4 mM
0 μM +++ +++ +++ +++ +++ + -
25 μM +++ +++ +++ + 0.66 - -
50 μM +++ +++ +++ 0.58 - - -
100 μM +++ +++ + - - - -
200 μM +++ +++ 0.71 - - - -
250 μM +++ ++ - - - - -
300 μM +++ 0.75 - - - - -
600 μM - - - - - - -
  1. *Concentrations for H2O2 are shown in horizontal rows; concentrations for I2 are shown in vertical rows. The absence of growth is indicated by the sign “-“. FICs index values are shown as numbers near correspondent “-“ sign. Signs “+++”, “++” and “+” indicate different degrees of growth. The results were recorded after 2 days of cultivation at 30°C (for S. cerevisiae), or after 1–2 days of cultivation at 37°C (for E. coli, S. aureus and P. aeruginosa).