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Table 3 Toxicities during induction chemotherapy

From: Randomized Phase II trial of paclitaxel and carboplatin followed by gemcitabine switch-maintenance therapy versus gemcitabine and carboplatin followed by gemcitabine continuation-maintenance therapy in previously untreated advanced non-small cell lung cancer

 

arm A (n = 25)

arm B (n = 24)

Grade

1

2

3

4

1

2

3

4

Leukopenia

1

2

1

-

-

2

2

1

Neutropenia

-

-

8

9

-

1

5

4

Neutropenic fever

-

-

1

-

-

-

-

-

Thrombocytopenia

-

-

-

-

1

4

1

2

Amenia

1

-

-

-

-

-

1

-

Low Hemoglobin

-

-

-

-

1

2

-

-

AST/ALT

3

2

1

-

-

2

3

-

Nausea

3

1

-

-

3

1

-

-

Pain

-

-

-

-

1

1

-

-

Arthralgia

2

2

-

-

-

-

-

-

Myalgia

2

3

-

-

-

-

-

-

Skin rash

1

2

1

-

1

2

1

-

Conspitation

2

-

-

-

3

-

-

-

Fever

2

-

-

-

-

2

-

-

Fatigue

3

1

-

-

1

1

-

-

Peripheral Neurotoxicies

2

1

2

-

-

-

-

-

Pruritus

-

1

-

-

-

1

-

-

Appetite loss

1

2

-

-

1

1

-

-