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Table 4 All toxicities of grade 1-4 and severe toxicities of grade 3-4 during gemcitabine maintenance

From: Randomized Phase II trial of paclitaxel and carboplatin followed by gemcitabine switch-maintenance therapy versus gemcitabine and carboplatin followed by gemcitabine continuation-maintenance therapy in previously untreated advanced non-small cell lung cancer

 

ALL (n = 20)

arm A (n = 12)

arm B (n = 8)

 

G1-4

G3-4

G1-4

G3-4

G1-4

G3-4

Leukopenia

1

-

1

-

-

-

Neutropenia

6

5

3

3

3

2

Thrombocytopenia

3

1

3

1

-

-

reduced Hb

1

-

-

-

1

-

Anemia

1

-

1

-

-

-

Peripheral neurotoxicities

1

-

1

-

-

-

Skin rash

1

-

1

-

-

-

Fever

1

-

1

-

-

-

Pain

1

-

-

-

1

-

Cutaneous injection reaction

1

-

-

-

1

-

Liver abnormality

2

-

2

-

-

-

Complicated pneumonia

1

-

1

-

-

-