Table 1 List of important diseases caused by mutations of the LMNA gene
From: Cardioembolic stroke related to limb-girdle muscular dystrophy 1B
Disease (and its acronym) | Inheritance pattern |
|---|---|
Striatal muscle involvement | Â |
Emery-Dreifuss muscular dystrophy (AD-EDMD) | AD |
Limb-girdle muscular dystrophy 1B (LGMD-1B) | AD |
Dilated cardiomyopathy and conduction-system disease (DCM-CD) | AD |
Peripheral neuropathy | Â |
Charcot-Marie-Tooth disease type 2B1 (CMT-2B1) | AR |
Partial lipodystrophy syndrome | Â |
Familial partial lipodystrophy, Dunnigan type (FPLD2) | AD |
Mandibuloacral dysplasia I (MAD1) | AR |
Premature aging | Â |
Hutchinson–Gilford progeria syndrome (HGPS) | AD |
Atypical Werner’s syndrome (AWRN) | AD |