Table 1 Median z-scores and average predicted folding free energy for influenza B (+)RNA, (−)RNA and synonymous codon mutant (mut (+)RNAs)
Segment | Z-score (+)RNA | Z-score Mut (+)RNA | Z-score (−)RNA | ΔG°37(+)RNA | ΔG°37Mut (+)RNA | ΔG°37(−)RNA | |
|---|---|---|---|---|---|---|---|
5 | NP | −2.0 | −0.7 | −1.2 | −494.5 | −493.5 | −485.7 |
8 | NS | −1.6 | −0.6 | −1.0 | −279.4 | −283.1 | −264.5 |
2 | PB1 | −1.6 | −0.8 | −1.8 | −601.7 | −624.1 | −580.9 |
1 | PB2 | −1.3 | −0.7 | −1.2 | −600.6 | −638.2 | −538.2 |
7 | M1/BM2 | −0.3 | −0.2 | 1.1 | −276.6 | −290.8 | −245.6 |
4 | HA | 0.0 | −0.3 | 0.0 | −485.1 | −511.4 | −506.7 |
3 | PA | 0.2 | −0.1 | −0.6 | −552.0 | −593.0 | −501.3 |
6 | NA | 1.1 | 0.6 | 1.2 | −384.2 | −409.5 | −374.8 |