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Table 1 Median z-scores and average predicted folding free energy for influenza B (+)RNA, (−)RNA and synonymous codon mutant (mut (+)RNAs)

From: Influenza B virus has global ordered RNA structure in (+) and (−) strands but relatively less stable predicted RNA folding free energy than allowed by the encoded protein sequence

Segment Z-score (+)RNA Z-score Mut (+)RNA Z-score (−)RNA ΔG°37(+)RNA ΔG°37Mut (+)RNA ΔG°37(−)RNA
5 NP −2.0 −0.7 −1.2 −494.5 −493.5 −485.7
8 NS −1.6 −0.6 −1.0 −279.4 −283.1 −264.5
2 PB1 −1.6 −0.8 −1.8 −601.7 −624.1 −580.9
1 PB2 −1.3 −0.7 −1.2 −600.6 −638.2 −538.2
7 M1/BM2 −0.3 −0.2 1.1 −276.6 −290.8 −245.6
4 HA 0.0 −0.3 0.0 −485.1 −511.4 −506.7
3 PA 0.2 −0.1 −0.6 −552.0 −593.0 −501.3
6 NA 1.1 0.6 1.2 −384.2 −409.5 −374.8
  1. Negative z-scores below −0.67 reveal GORS.