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Table 3 Risk factors in total population, in group with and without cardiac complications

From: Cardiac safety of the adjuvant Trastuzumab in a Moroccan population: observational monocentric study of about 100 patients

Risk factor

Total population

Group with cardiac complications

Group with no cardiac complications

Value of p no complications vs complications

 

N = 100

N = 38

N = 62

 

Age (years)

46

47

45

0.96

Overweight

38%

12 (31.57%)

26 (41.93%)

0.61

obesity

35%

16 (42.10%)

19 (30.64%)

0.57

Hypertension

11%

4 (10.52%)

7 (11.29%)

0.88

Diabetes

7%

3 (7.89%)

4 (6.45%)

0.31

LVFE baseline

70%

74%

67%

< 0.001

Chemotherapy with or without anthracycline

100%

Sequential

25 (65.5%)

Sequential

35 (56.5%)

0.3

anthracycline

13 (34.5%)

anthracycline

27 (43.5%)

Nb of anthracycline cycles

4

4

4

0.61

Concomitant radiotherapy with trastuzumab

69

24 (63%)

45 (72%)

0.318