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Table 1 Demographic and clinical data of patients with Mild Cognitive Impairment (MCI) and B12 deficiency compared with patients with MCI and normal vitamin B12 levels

From: Do MCI patients with vitamin B12 deficiency have distinctive cognitive deficits?

 

MCI vitamin B12 deficiency (n=15)

MCI normal vitamin B12 (n=45)

P- value

Age, years [mean ± SD (range)]

74.9±7.6

74.9±6.9

1.00

Sex, female/male (n)

7/8

22/23

1.00

Formal education, years (mean ± SD)

6.7±4.6

7.4±4.8

0.66

Vitamin B12 level, pg/mL (mean ± SD)

148.4±42.7

496.9±218.9

<0.001*

Duration of cognitive complaints (mean ± SD)

1.2±1.0

3.4±3.0

<0.001*

Depressive symptoms, geriatric depression scale (mean ± SD)

3.6±1.5

4.1±2.9

0.59

Drugs with possible effect on cognition (n)

0

5

0.32

Response to vitamin B12 therapy, Yes/No/Unknown (n)

0/14/1

NA

 
  1. Student’s t-test, Fisher’s exact test; *Statistically significant (p< 0.05), NA not applicable