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Figure 2 | BMC Research Notes

Figure 2

From: An atypical case of lymphoproliferative pulmonary involvement in a patient with Sjögren’s syndrome: a case report

Figure 2

A lung biopsy specimen of the left lower lobe, showing mild and homogeneous interstitial pneumonia, with the presence of numerous lymphoid follicles and no definite nuclear atypicality in the lymphocytes [hematoxylin-eosin stain; magnification ×40 (A), ×100 (insert upper), ×400 (insert lower): the boundary part between the lymphoid follicle (lower right) and surrounding tissue]. The immunohistochemical staining for L26, showing exclusively B-lymphocytes within the lymphoid follicles that exhibited a brownish reaction product [magnification ×40 (B), ×100 (insert)]. The immunohistochemical staining for bcl-2, showing the distribution of bcl-2 positive lymphocytes around the centers of lymphoid follicles (reactive hyperplasia pattern) [magnification ×40 (C), ×100 (insert)]. The immunohistochemical staining for UCHL-1, showing diffusely distributed T-lymphocytes in the alveolar walls or around the lymphoid follicles [magnification ×40 (D), ×100 (insert)].

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