Figure 2

Sequence analysis of novel variant 3D. A, Part of the transcript sequence was shared between exons 3 and 7 in novel variant 3D. The shared bases are shown in bold characters. Regions that matched with exon 3 and 7 are indicated by solid and dashed line, respectively. Uppercase bases (AGGC) indicate potential splice site that allow the generation of GC-AG introns. B, Prediction of splice site between novel exons 3 and 7. Exons and introns are indicated in gray and white boxes, respectively. Variant 3D and GC-AG introns were generated by alternative splicing of the potential splice site.