Serial EM sections of liver tissue showing the presence of a cytoplasmic lipid droplet surrounded by the nucleus. This series of 6 consecutive sections is a sample of the whole series (the whole stack consisted of 56 sections). The white arrows in A, B, C and D show contact between the LD and the cytoplasm. The black arrow in E indicates that the LD is also in contact with the nuclear envelope in this particular section. In electron micrograph in F, the LD appears to be completely surrounded by the nucleus, with a small portion of cytoplasm between the LD and the nuclear envelope. ld: lipid droplet; n: nucleus; cy: cytoplasm.