Table 2 Allele frequencies and genotype distribution for the TGFB1 polymorphisms in CD patients and controls
From: Polymorphisms of the cytokine genes TGFB1 and IL10 in a mixed-race population with Crohn’s disease
91 Cases n (%) | 91 Controls n (%) | OR | [99.8% CI] | P B | P value | |
|---|---|---|---|---|---|---|
• rs1800470 (codon 10 T > C) | ||||||
T allele | 81 (45.5%) | 116 (63.7%) | 2.19 | [1.10- 4.42] | 0.005 | 0.001 |
C allele | 101 (55.5%) | 66 (36.3%) | ||||
• Genotype | ||||||
TT | 22 (24.1%) | 39 (42.8%) | Reference | |||
TC | 37 (40.7%) | 38 (41.8%) | 1.73 | [0.66- 4.78] | 0.820 | 0.164 |
CC | 32 (35.2%) | 14 (15.4%) | 4.05 | [1.31- 13.20] | 0.005 | 0.001 |
• rs1800471 (codon 25 G > C) | ||||||
G allele | 166 (91.2%) | 176 (96.7%) | 2.83 | [0.77-10.89] | 0.150 | 0.030 |
C allele | 16 (8.8%) | 6 (3.3%) | ||||
• Genotype | ||||||
GG | 77 (84.6%) | 85 (93.4%) | Reference | |||
GC | 12 (13.2%) | 6 (6.6%) | 2.21 | [0.53-11.08] | 0.710 | 0.142 |
CC | 2 (2.2%) | 0 (0%) | ¨¨¨¨¨ | ¨¨¨¨¨¨ | ........ | ¨¨¨¨¨¨ |