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Table 2 Allele frequencies and genotype distribution for the TGFB1 polymorphisms in CD patients and controls

From: Polymorphisms of the cytokine genes TGFB1 and IL10 in a mixed-race population with Crohn’s disease

  91 Cases n (%) 91 Controls n (%) OR [99.8% CI] P B P value
• rs1800470 (codon 10 T > C)      
T allele 81 (45.5%) 116 (63.7%) 2.19 [1.10- 4.42] 0.005 0.001
C allele 101 (55.5%) 66 (36.3%)     
• Genotype       
TT 22 (24.1%) 39 (42.8%) Reference    
TC 37 (40.7%) 38 (41.8%) 1.73 [0.66- 4.78] 0.820 0.164
CC 32 (35.2%) 14 (15.4%) 4.05 [1.31- 13.20] 0.005 0.001
• rs1800471 (codon 25 G > C)      
G allele 166 (91.2%) 176 (96.7%) 2.83 [0.77-10.89] 0.150 0.030
C allele 16 (8.8%) 6 (3.3%)     
• Genotype       
GG 77 (84.6%) 85 (93.4%) Reference   
GC 12 (13.2%) 6 (6.6%) 2.21 [0.53-11.08] 0.710 0.142
CC 2 (2.2%) 0 (0%) ¨¨¨¨¨ ¨¨¨¨¨¨ ........ ¨¨¨¨¨¨
  1. n (%) Number of alleles or genotypes (percent).
  2. P B Bonferroni adjustment.
  3. ¨¨¨¨¨¨ Insufficient number.