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Table 3 Allele frequencies and genotype distribution for the IL10 polymorphisms in CD patients and controls

From: Polymorphisms of the cytokine genes TGFB1 and IL10 in a mixed-race population with Crohn’s disease

 

91 cases n (%)

91 controls n (%)

OR

[99% CI]

P value

• rs1800896 (−1082 A > G)

    

Aallele

116 (63.7%)

123 (67.6%)

1.19

[0.66- 2.14]

0.44

G allele

66 (36.3%)

59 (32.4%)

   

• Genotype

     

AA

41 (45.0%)

40 (44.0%)

Reference

  

GA

34 (37.4%)

43 (47.2%)

0.77

[0.32- 1.84]

0.42

GG

16 (17.6%)

8 (8.8%)

1.95

[0.52- 7.45]

0.16

• rs1800871 (−819 T > C)*

    

C allele

116 (63.7%)

106 (58.2%)

0.79

[0.45-1.41]

0.28

Tallele

66 (36.3%)

76 (41.8%)

   

• Genotype

     

CC

36 (39.6%)

28 (30.8%)

Reference

 

CT

44 (48.4%)

50 (54.9%)

0.68

[0.28-1.66]

0.24

TT

11 (12.0%)

13 (14.3%)

0.66

[0.17-2.46]

0.38

  1. n(%) Number of alleles or genotypes (percent).
  2. *SNPs rs1800871 and rs1800872 were in 100% linkage disequilibrium.