Table 1 Tumor and demographic charcateristics of 79 patients with diabetes treated with glargine and other types of insulin
Factor | Subgroup | Patients on glargine | Patients on other types of insulin | p-value |
|---|---|---|---|---|
(N = 13) | (N = 66) | |||
Median age (years) | 63 | 67 | 0.30 | |
Median tumor size (mm) | 22 | 20 | 0.93 | |
Median BMI (kg/m 2 ) | 28.6 | 29.75 | 0.51 | |
Median ASA score | 2 | 2 | 0.95 | |
Median number of metastatic lymph nodes | 1 | 1 | 0.58 | |
Mitoses (Median) | 2 | 2 | 0.72 | |
Age (years) | 70 or less | 10 | 42 | 0.52 |
71 or more | 3 | 24 | ||
BMI (kg/m 2 ) | less than 30 | 2 | 12 | 0.74 |
(N = 76) | 30 or more | 10 | 52 | |
American Society of Anesthesiologists score | 1 | 0 | 1 | 0.89 |
2 | 7 | 34 | ||
(N = 74) | 3 | 5 | 27 | |
Contralateral breast carcinoma | No | 13 | 64 | 1.00 |
Yes | 0 | 2 | ||
Another malignancy | No | 12 | 58 | 1.00 |
Yes | 1 | 8 | ||
Type of diabetes mellitus | DM type 1 | 4 | 10 | 0.23 |
DM type 2 | 9 | 56 | ||
Therapy with metformine | No | 11 | 54 | 1.00 |
Yes | 2 | 12 | ||
Therapy with sulfonylurea | No | 12 | 58 | 1.00 |
Yes | 1 | 8 | ||
pT tumor stage | pT1 | 5 | 31 | 0.22 |
pT2 | 6 | 14 | ||
pT3 | 1 | 4 | ||
pT4 | 1 | 17 | ||
T3 or T4 stage | pT1 or pT2 | 11 | 45 | 0.32 |
pT3 or pT4 | 2 | 21 | ||
N stage | pN0 | 6 | 28 | 0.80 |
pN1 or pN2 | 7 | 38 | ||
Number of metastatic lymph nodes | 0 | 6 | 28 | 0.95 |
1–3 | 4 | 20 | ||
4 or more | 3 | 18 | ||
M stage | M0 | 12 | 62 | 1.00 |
M1 | 1 | 4 | ||
Type of invasive carcinoma | Ductal | 10 | 57 | 0.41 |
Lobular or other types | 3 | 9 | ||
Tumor differentiation | Well or moderate | 6 | 35 | 0.65 |
Poor | 7 | 31 | ||
Estrogen hormone status (10% or more) | Positive | 10 | 61 | 0.12 |
Negative | 3 | 5 | ||
Progesteron hormone status (10% or more) | Positive | 8 | 49 | 0.35 |
Negative | 5 | 17 | ||
HER-2 | Negative | 13 | 62 | 1.00 |
Positive | 0 | 4 |