Table 2 Biochemical, virological, histological and immunological parameters before and after a 24-week course of PEG-IFN-α-2a and ribavirin in a CHC patient who developed post-treatment RA
Pretreatment | Post-treatment | |
|---|---|---|
AST (IU/mL) | 66 | 25 |
ALT (IU/mL) | 84 | 19 |
HCV RNA (IU/mL) | 660,000 | negative |
Liver histology | A2/F2 | A1/F1 |
METAVIR grading/staging | ||
Erythrocyte sedimentation rate (1st hour) | 11 | 76 |
C-reactive protein (mg/dL) | 0.35 | 2.21 |
Rheumatoid Factor | negative | positive |
Anti-CCP Antibodies (IU/ml) | negative | 860 |
Antinuclear Antibodies | negative | 1/320 |
Anti-dsDNA Antibodies | negative | negative |
Cryoglobulin | negative | negative |